Senior Research Associate, Flow Cytometry

Company Overview:

Beam Therapeutics is a biotechnology company committed to establishing the leading, fully integrated platform for precision genetic medicines. To achieve this vision, Beam has assembled a platform with integrated gene editing, delivery and internal manufacturing capabilities. Beam’s suite of gene editing technologies is anchored by base editing, a proprietary technology that is designed to enable precise, predictable and efficient single base changes, at targeted genomic sequences, without making double-stranded breaks in the DNA.

This has the potential to enable a wide range of therapeutic editing strategies that Beam is using to advance a diversified portfolio of base editing programs. Beam is a values-driven organization committed to its people, cutting-edge science, and a vision of providing life-long cures to patients suffering from serious diseases.

• Supporting all internal/external research programs.
• Execute specimen preparation, staining and sample acquisition of flow cytometric data.
• Perform cell sorting on BD FACS Melody, FACSAria Fusion or BD FACS Symphony S6.
• Design, plan, and execute assay development and/or platform development within the core flow cytometry group and cross-functionally.
• Perform flow data analyses and interpretation, and present data at group meetings.
• Maintain electronic notebook record of performed experiments.
• Provide basic training to researcher on various flow cytometers and cell sorters.
• Evaluate and troubleshoot instrument issues.
• Assist in coordinating core lab logistics (e.g. user scheduling, vendor/maintenance calls, etc.)

• Bachelor’s degree (or foreign equivalent) with five years of progressive, post-baccalaureate experience, or a master’s degree (or foreign equivalent) with two years of progressive, post-baccalaureate experience, with degree fields in biology, immunology, cell biology, molecular biology, pharmaceutical sciences, biochemistry, biomedical engineering, biotechnology or a closely related field, and demonstrated experience in all of the following:

(a) performing high-parameter flow cytometry analyses of hematopoietic stem and immune cell subsets, and,

(b) designing and executing flow-based assay development for preclinical or translational research; and,

(c) conducting quantitative flow cytometry data analysis using Flow Jo or FCS Express; and,

(d) troubleshooting instrument performance and coordinating maintenance; and,

(e) operating and maintaining high-parameter flow cytometers and cell sorters.

• Permanent, full-time, immediately available, job opportunity;

• Does not require travel (role is substantially laboratory-based, in-house);

• Not permitted to telecommute, i.e., cannot exclusively work remotely from home;

• Must live in the City of Cambridge, MA, or within a reasonable, daily commuting distance thereof (e.g., areas contemplated can include the City of Boston, the larger Greater Boston region, or Massachusetts’ Metro West, North or South Shore communities);

• Beam’s headquarters is at 238 Main Street, Cambridge, MA 02142 and this is the primary worksite for the role long-term; and

• Role is not a supervisory role and does not have subordinate, direct reports. This is a hands-on, individual contributor position.

$95,000—$115,000 USD