Head of Agentic Biology

** About the job
** The Computational and AI Strategy – R&D (CompAI) is a new function within Sanofi that brings together a multidisciplinary team of  bilinguals  — scientists and engineers with deep domain expertise and AI skills — across verticals including computational biology, molecular design, molecular engineering, safety, and manufacturing. CompAI is at the forefront of Sanofi's ambition to become the most AI-powered biopharma in the world, embedding cutting-edge computational capabilities directly into the heart of drug discovery and development.

We are seeking a visionary, highly collaborative, and deeply technical leader to step into the role of
** Head of Agentic Biology
** within the Computational Biology group  an era where biology is rapidly becoming an information science, this forward-thinking role is designed to transform early discovery research  using an AI-first mindset. Moving beyond traditional, reactive data analysis, the Head of Agentic Biology will collaboratively build an enterprise-scale computational ecosystem that accelerates end-to-end therapeutic area (TA) programs using an agentic approach. By closing the loop between automated wet-lab data capture and cutting-edge predictive modeling — including statistical methods, classical ML, language technologies, biological foundation models, and emerging agentic AI capabilities — this role will provide quantifiable insights that empower critical go/no-go portfolio decisions.

A primary goal is advancing the discovery of novel targets with a high degree of success and extendable therapeutic opportunities, based on the analysis of large volumes of multi-modal disease data — including genetics, genomics, cellular, clinical, and pathological data — in close collaboration with Sanofi's therapeutic areas: immunology and inflammation, oncology, neuroscience, rare diseases, and ophthalmology, and in integration with CompAI verticals.

Join the engine of Sanofi’s mission — where deep immunoscience meets bold, AI-powered research. In R&D, you’ll drive breakthroughs that could turn the impossible into possible for millions.
** About Sanofi
** We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.
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* Main Responsibilities:

**** Acceleration of Discovery using Agentic Biology
*** Lead the design and deployment of first-generation agentic bioinformatics workflows that automate end-to-end data capture, analysis, and insight generation across therapeutic programs.
* Drive the transition from reactive data analysis to proactive, predictive, and autonomous biological reasoning systems.
* Advance novel target discovery using multi-modal disease data including genetics, genomics, single-cell, proteomics, imaging, and clinical datasets.
** Leadership & Portfolio Impact
*** Serve as a leader in bioinformatics, providing strategic direction aligned with Sanofi's R&D priorities across immunology, inflammation, oncology, neuroscience, rare diseases, and ophthalmology leveraging agentic technologies.
* Deliver quantifiable computational insights that directly inform go/no-go portfolio decisions and accelerate target validation.
* Translate computational discoveries into experimental target validation strategies with a focus on target biology, drug repurposing, and indication expansion.
* Present complex data and strategic recommendations to senior leadership with clarity and scientific rigor.
** Infrastructure & Technology
*** Design, build,…