Senior Associate Scientist

Skill set – Oligonucleotide synthesis and downstream processing, Analytical HPLC/LCMS/UV-vis Clinical/Development - Senior Associate Scientist Summary of Key Responsibilities

• Hands‑on lab support and process development for the chemical synthesis and downstream processing of oligonucleotide‑based drug substance
• Synthesis of oligonucleotides up to 11 mmol scale
• Downstream processing of oligonucleotides including prep‑HPLC, ultrafiltration, annealing, concentration and lyophilization
• In‑process analytical testing including AX‑HPLC, IPRP‑HPLC, LCMS, UV‑vis
• Technical support for optimization of contract manufacturing processes

• BS in Chemistry with 3+ years lab experience, preferably in an industrial setting.
• Basic understanding of analytical techniques (pH, osmolality, conductivity measurement, HPLC, LC‑MS etc.). Related hands‑on experience is preferred. Knowledge of oligonucleotide manufacture process including phosphoramidite chemistry, chromatography, ultrafiltration etc. is a plus.
• Experience in record‑keeping and excellent laboratory documentation practice, are required. Strong commitment to high laboratory and scientific standard; ability to maintain a safe, clean, and orderly laboratory work environment; assist in routine lab and equipment maintenance.
• Good communication skills are a must for this position. The successful candidate must be a responsible and proactive individual who is able to work as a team player in a highly dynamic environment with aggressive timelines.