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Senior Associate Scientist

Job in Cambridge, Middlesex County, Massachusetts, 02142, USA
Listing for: LanceSoft Inc
Seasonal/Temporary position
Listed on 2026-06-03
Job specializations:
  • Science
    Research Scientist, Biotechnology
Job Description & How to Apply Below
Job title :
Senior Associate Scientist

Location:

Cambridge, MA
Duration: 9 Months contract

Job description:
Job Summary of Key Responsibilities
  • Hands-on lab support and process development for the chemical synthesis and downstream processing of oligonucleotide-based drug substance
  • Synthesis of oligonucleotides up to 11 mmol scale
  • Downstream processing of oligonucleotides including prep-HPLC, Ultrafiltration, annealing, concentration and Lyophilization
  • In process analytical testing including AX-HPLC, IPRP-HPLC, LCMS, UV-vis
  • Technical support for optimization of contract manufacturing processes
Qualifications
  • BS in Chemistry with 3+ years lab experience, preferably in an industrial setting.
  • Basic understanding of analytical techniques (pH, osmolality, conductivity measurement, HPLC, LC-MS etc.). Related hands-on experience is preferred.
  • Knowledge of oligonucleotide manufacture process including phosphoramidite chemistry, chromatography, ultrafiltration etc. is a plus.
  • Experience in record-keeping and excellent laboratory documentation practice, are required. Strong commitment to high laboratory and scientific standard; ability to maintain a safe, clean, and orderly laboratory work environment; assist in routine lab and equipment maintenance.
  • Good communication skills are a must for this position. The successful candidate must be a responsible and proactive individual who is able to work as a team player in a highly dynamic environment with aggressive timelines.
Comment Skill set Oligonucleotide synthesis and downstream processing, Analytical HPLC/LCMS/UV-vis
Position Requirements
10+ Years work experience
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