Principal Scientist,Cancer Immunology Clinical Translational Research Cambridge Crossing

Position: Principal Scientist, Cancer Immunology Clinical Translational Research Cambridge Crossing - MA [...]
## Principal Scientist, Cancer Immunology Clinical Translational Research Cambridge Crossing - MA - US
* Serve as a key scientific stakeholder in early clinical trial programs.
* Design and develop biomarker, pharmacodynamic, and target engagement assays to understand drug mechanism of action and response.
* Interact with project teams and contract laboratories for the design, execution, and oversight of molecular, cellular, and/or in vivo studies.
* Collaborate with cross-functional teams and external partners (CROs, specialty labs) to generate high-quality biomarker data for clinical studies.
* Contribute to translational plans, sample collection strategies, and documentation for early-phase trials.
* Present experimental results and share scientific insights with project teams and stakeholders.
* Proactively provides insight into novel ways to incorporate biomarkers into clinical designs to enable early understanding of emerging drug profiles, as well as input around tumor types and potential impact of biomarkers on internal decision making.
* Provides oversight to progress validated biomarkers into development of diagnostic assays, as needed
* Participates in strategic review and input to presentations, publications and internal/ external communications along with accountable program leadership and in governance forums
* Develops solutions and courses of action for senior staff, including identification of risks and risk mitigations
* Shares expertise, experience, lessons learned and knowledge with translational and other relevant scientific experts and colleagues across the organization
- Bachelor's Degree
* 8+ years of academic and / or industry experience
- Master's Degree
* 6+ years of academic and / or industry experience
- Ph.D. or equivalent advanced degree in the Life Sciences
* 4+ of academic and / or industry experience
* PhD and 6+ years of industry experience in drug development, ideally with at least 3 years in clinical translational research or translational medicine.
* Strong immunology experience, with an emphasis on solid tumor biology preferred.
* Experience in oncology translational biomarker roles, with solid tumor and immune-oncology expertise strongly preferred.
* Strong scientific acumen and mechanistic understanding of disease biology, with demonstrated contributions to oncology and immuno-oncology drug development.
* Hands-on experience designing, executing, and analyzing translational biomarker assays and data across multiple technologies (e.g., genomics, immunohistochemistry, flow cytometry, immunoassays) and sample types in clinical studies.
* Familiarity with the drug development process and experience collaborating with clinical teams; able to communicate results and contribute to discussions in cross-functional settings.
* Demonstrated ability to work effectively with internal stakeholders and external partners (e.g., CROs, specialty labs).
* Excellent communication, organizational, and teamwork skills, with a proactive and collaborative mindset.
* Eagerness to learn, grow, and take on increasing responsibility in a fast-paced environment.

The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee's work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience.

Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit
* ** Health Coverage:
** Medical, pharmacy, dental, and vision care.
* ** Wellbeing Support:
** Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
* ** Financial Well-being and Protection:
** 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and…