Scientific Associate Director, Oncology Translational Research

Scientific Associate Director, Oncology Translational Research

Reports to Scientific VP, Head of Translational Research (Oncology). Leads translational strategy and execution for early-stage oncology programs, focusing on biomarker development, patient stratification, and mechanism-of-action and resistance insights.

• Lead translational and clinical biomarker strategy and plan (patient stratification, target engagement, pharmacodynamics, mechanisms of action/resistance) for assigned solid tumor oncology early clinical development programs.
• Provide scientific subject‑matter expertise, integrating translational research with clinical development plans, generating and analyzing data, and communicating findings to the development team and matrix leadership.
• Collaborate with discovery, clinical, precision medicine, regulatory, medical, and commercial stakeholders in a highly matrixed environment.
• Build and maintain cross‑disciplinary relationships, participate in decision‑making to support R&D portfolio goals.
• Identify risks and develop innovative solutions, including new approaches and technologies, to address novel challenges.

• Bachelor’s Degree with 12+ years of academic and/or industry experience.
• Master’s Degree with 10+ years of academic and/or industry experience.
• Ph.D. or equivalent advanced degree in the Life Sciences with 8+ years of academic and/or industry experience.
• Minimum 4+ years of matrix leadership experience.

• Ph.D., MD or Ph.D./MD in Oncology, Immunology or related fields.
• 5–8+ years of industry experience.
• 3–5 years of experience in clinical development, oncology biomarker strategy and implementation.
• Deep knowledge of current and evolving competitive landscape in Cancer Immunology (multi‑specific and T‑cell engager).
• Working knowledge of various technical platforms tailored for clinical biomarkers.
• Experience authoring or reviewing regulatory documents.
• Proven publication record (manuscripts, conference presentations).
• Excellent verbal and written communication skills.
• Experience with external partners and familiarity with foreign regulations, agencies and clinical research landscape.
• Domestic and international travel as needed.

Cambridge Crossing: $214,020 – $259,344 annual salary. Additional incentive cash and stock opportunities may be available. Final compensation determined by demonstrated experience.

• Health coverage: medical, pharmacy, dental and vision.
• Well‑being support programs.
• 401(k) plan, disability, life insurance and other financial protections.
• Paid time off, flexible time, national holidays and additional leave options.
• Global shutdowns and summer hour flexibility for eligible employees.

We are an equal opportunity employer and welcome applicants from all backgrounds.