Senior Scientist, Analytical Development

Position Summary

Seeking a motivated and skilled Senior Scientist to join the Analytical Development team. The successful candidate must possess extensive scientific knowledge and hands‑on experience in cell biology/immunology and/or RNA therapeutics. The candidate will collaborate with the research team, delivery team, process development, and other CMC groups to develop novel bioassays, including potency assays, and conduct method transfer and qualification activities.

• Manage the development and pre‑qualification of multiple cell‑based assays for RNA/LNP drug substance and drug product.
• Coordinate with colleagues within analytical development and research group to transfer phase‑appropriate methods to external testing labs for GMP release testing and stability program.
• Work as subject‑matter expert to ensure potency assays are implemented at external QC testing labs with technical support, including troubleshooting potential issues during transfer and qualification.
• Draft and review development reports, testing methods, SOPs, and assist in preparation of CMC regulatory filings.
• Onboard new bioassays and improve existing assay performance with other SMEs.
• Collaborate and communicate data effectively through internal and external partners.
• Lab‑based contract position.

• Ph.D. or M.S. in cell biology, molecular biology, biochemistry or related discipline.
• Minimum 2 years experience in CAR‑T cell therapy and/or related area.
• Hands‑on experience with multiple immortalized and primary cell lines, and extensive experience in characterization of immune cells using flow cytometry and other functional assays.
• Hands‑on experience in flow cytometry required.
• Experience with biochemical assays such as ELISA, Western blot, qPCR, etc. desired.
• Experience with assay transfer and qualification from development lab to external testing labs for early‑stage program desired.
• Strong problem‑solving skills and ability to work independently and in a team in a startup environment preferred.
• Track record of consistently meeting deadlines in a dynamic, fast‑paced environment.
• Detail‑oriented in assay development and documentation in a regulatory environment desired.

Cambridge, MA – $132,330 – $160,350 per year. The starting compensation range is for full‑time employees. Additional incentive cash and stock opportunities may be available. Final individual compensation will be decided based on demonstrated experience.

Benefit offerings are subject to the terms and conditions of the applicable plans in effect at the time and may require enrollment. Our benefits include:

• Health Coverage: Medical, pharmacy, dental and vision care.
• Well‑being Support: Programs such as BMS Well‑Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
• Financial Well‑being and Protection: 401(k) plan, short‑ and long‑term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support and survivor support.
• Paid Time Off: US Exempt Employees flexible time off (unlimited with manager approval), 11 paid national holidays, etc. Additional time off may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement and military needs and an annual Global Shutdown between Christmas and New Years Day.

Cambridge, MA

Bristol Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, pregnancy, citizenship, marital status, gender expression, genetic information, political affiliation, or any other characteristic protected by law.