Director, Clinical Sciences, Oncology

The Role

This role will support Oncology Therapeutic programs, specifically supporting the Clinical Study Lead in the development, execution and evaluation of Phase 1-3 clinical studies. The principal responsibility is to ensure comprehensive data quality to support internal governance decisions and regulatory submissions.

• Oversee end‑to‑end delivery of clinical trial protocols, including study design, initiation, medical safety data monitoring, data dissemination and close‑out activities.
• Collaborate with Clinical Operations in the startup of global clinical studies to ensure on‑schedule site activation and subject enrollment.
• Design and implement clinical study parameters to minimize operational risk and increase study site performance and efficiency.
• Contribute to inspection readiness activities that support audits and regulatory inspections related to clinical trial conduct.
• Perform and coordinate clinical data review and analysis of study data, including review of case report forms, data listings, medical coding and patient profiles to ensure proper verification of clinical data.
• Provide review and interpretation of clinical data and ensure timely execution of deliverables in collaboration with the Clinical Trial Team and external partners.
• Support managing study sites to ensure that treatment discontinuation or safety decisions are made in alignment with the protocol.
• Assist in the development of content for Investigator Meetings, investigator engagements and Advisory Board meetings.
• Author and review clinical study documents in compliance with regulatory standards, including protocols, informed consent documents, DSURs and clinical components of investigator brochures, INDs and marketing applications.
• Support and help drive the evolution of the clinical science role and participate in continuous improvement initiatives related to the clinical trial delivery operating model.

• PhD, PharmD, master’s or advanced nursing degree with significant scientific and clinical oncology knowledge.
• Minimum of 8 years of clinical development experience within a pharmaceutical or biotechnology company.
• Significant experience ensuring clinical trial data integrity, data analysis (including exploratory analyses) and data presentation.
• Experience with Medidata Rave and clinical data analytics platforms such as Elluminate or Spotfire (preferred).
• Excellent written, oral, and presentation communication skills.
• Ability to travel up to 15% for study sites and scientific congresses.
• Strong teamwork and interpersonal skills, with a demonstrated ability to work effectively in a matrix environment.
• Personal and professional commitment to the highest ethical standards.

• High‑performing, self‑motivated and energetic individual with outstanding scientific and clinical oncology knowledge.
• History of operating successfully in a matrix environment with highly developed interpersonal and communication skills.
• Capability to contribute to both early and late‑stage clinical development programs in collaboration with Drug Discovery, Translational Medicine, Regulatory Affairs, Biostatistics, Medical Affairs and Commercial.

The salary range for this role is $ – $. The successful candidate may be eligible for an annual discretionary bonus, other incentive compensation or equity award, subject to company plan eligibility criteria and individual performance.

Benefits include:

• Best‑in‑class healthcare coverage, plus voluntary benefit programs.
• Holistic well‑being support: fitness, mindfulness and mental health resources.
• Family planning benefits, including fertility, adoption and surrogacy support.
• Generous paid time off (vacation, volunteer days, sabbatical, global recharge days, discretionary year‑end shutdown).
• Savings and investment opportunities.
• Location‑specific perks and extras.

Moderna is committed to equal employment opportunity and non‑discrimination for all employees and qualified applicants without regard to race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability,…