Associate Director, Clinical Supply Chain Management

Company

Summary:

Korro is a biopharmaceutical company focused on developing a new class of genetic medicines for both rare and highly prevalent diseases using its proprietary RNA editing platform. Korro is generating a portfolio of differentiated programs that are designed to harness the body’s natural RNA editing process to effect a precise yet transient single base edit. By editing RNA instead of DNA, Korro is expanding the reach of genetic medicines by delivering additional precision and tunability, which has the potential for increased specificity and improved long‑term tolerability.

Using an oligonucleotide-based approach, Korro expects to bring its medicines to patients by leveraging its proprietary platform with precedented delivery modalities, manufacturing know-how, and established regulatory pathways of approved oligonucleotide drugs. Korro is based in Cambridge, Massachusetts.

We are collaborative and united by a common mission. We are building a company with extraordinary people with an audacious vision to create transformative genetic medicines for prevalent diseases. Our values – Rewrite the future, On the Cutting Edge, Better Together, Dynamically Different, Kindness and Integrity – form the fabric of the organization. They are reinforced daily and serve as key dimensions in the hiring process to help us ensure that Korro is a magnet for outstanding talent and a great place to work.

Join us as we redefine what’s possible in genetic medicine and work to make a lasting impact on human health.

The position will lead the strategic and operational management of complex clinical supply activities across all phases of development to provide life‑changing therapeutics for patients. The ideal candidate will bring deep expertise in supply chain strategy and vendor oversight, with a strong understanding of global GMP and regulatory requirements, and ensures uninterrupted, compliant, and cost‑effective delivery of investigational products to global clinical trial sites.

This role collaborates with Clinical Operations/Development, Quality, Regulatory Affairs, and external partners to manage supply planning, inventory management, and distribution & logistics aligned with GMP and regulatory guidelines.

Excellent written and oral communication skills are required, as is the desire and ability to work in a small, fast‑paced, and patient‑focused environment.

• Develop and implement end‑to‑end supply chain strategies from raw material to finished goods, aligned with corporate and clinical development goals.
• Work closely with clinical operations/development to develop clinical forecasts/demand plans based on clinical trial requirements, while optimizing supply chain operations to ensure timely availability of investigational medicinal product (IMP)/clinical trial material (CTM).
• Establish and manage vendor relationships for outsourced supply chain services. Develop budget and track invoices to contracts.

• Manage labeling, packaging, distribution, and returns of IMP/CTM with external vendors in compliance with GMP and global regulations.
• Manage creation of label text/translation and design of study drug packaging in compliance with country‑specific regulations and study requirements.
• Develop Interactive Response Technology (IRT) supply & return strategy, lead/oversee the IRT set up, and participate in User Acceptance Testing (UAT) where needed.
• Develop requirements/specifications for clinical study drug and other drug supply as required, including packaged product specifications and product shipping & storage specifications.
• Ensure on time delivery of clinical supplies to depots and clinical sites globally, in compliance with clinical protocol and country specific regulations/requirements.
• Actively monitor IMP inventory levels at global depots & clinical sites and coordinate resupply to prevent stockouts.
• Author study specific pharmacy manuals and supply related training/instructional materials (e.g. IM and SIV slides, dosing cards, accountability forms).

• Oversee shipping & handling of temperature‑sensitive DS/DP/IMP & related…