Software Engineer, Backend Developer, Front End Developer

Overview

The Research Informatics group is looking for a software engineer to develop, maintain, and support web applications and tools utilized by Research, Early Development, and other groups within Alnylam. These tools directly support the discovery and development of RNAi therapeutics, enabling scientists to analyze data, make decisions, and accelerate progress toward new medicines. Because RNAi is a relatively new therapeutic modality, much of our work involves building custom software, ranging from data pipelines and APIs to user-facing applications and visualizations.

We are also expanding our internal AI platform, including tools for natural language querying, structured data access (e.g., text-to-SQL), and working with unstructured data. Engineers on the team contribute to these systems and help integrate them into scientific workflows. This role is a good fit for someone early in their career who has some professional experience and is excited to take on increasing ownership, contribute to real-world scientific problems, and grow within a collaborative engineering team.

This position is hybrid
and will be primarily located in Cambridge, MA.

• Work with scientists and internal users to understand needs and help design and implement software solutions
• Build, test, debug, and maintain web applications, APIs, and data-driven tools
• Ability to work independently on well-defined tasks and collaborate on more complex projects
• Contribute to the design and improvement of existing systems and workflows
• Write clear documentation (design notes, technical specs, diagrams)
• Participate in code reviews and follow established engineering best practices
• Collaborate with the team through agile ceremonies (standups, sprint planning)

• BS in Computer Science or equivalent experience
• 1-3 years of professional software development experience
• Strong fundamentals in programming, debugging, unit testing, and problem solving
• Familiarity with version control (Git)
• Understanding of web application architecture (client/server interactions, APIs)
• Experience with one or more of the following:
  • Python
  • JavaScript / Type Script
  • SQL

• Experience with any of these frameworks/tools is a plus
  • Flask or similar backend frameworks
  • React or modern frontend frameworks
  • AWS or other cloud platforms
  • SQL Alchemy or ORM tooling
  • Docker or containerization
• Exposure to AI-powered tools or data workflows
• Familiarity with agile methodologies

• Strong communication skills and ability to work with both technical and non-technical stakeholders
• Eagerness to learn and grow in a collaborative environment

Engineers on this team regularly see their work used directly by scientists and researchers.

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