Director, Manufacturing

Preparedness today, safer tomorrow.

Emergent is a leading public health company that delivers protective and life-saving solutions to

communities around the world. Here, you will join passionate professionals where our culture is informed

by our values and commitment to protecting and saving lives.

Job Summary

The Director of Manufacturing Operations is a senior site leader responsible for end-to-end execution and performance of commercial vaccine drug substance (DS) manufacturing operations at the Canton, MA site. This role has full accountability for upstream and downstream processing, central services (buffer and solution preparation), equipment and component preparation, and detailed manufacturing scheduling within a GMP commercial manufacturing environment. The Director ensures safe, compliant, and reliable operations while delivering throughput, cost, and supply performance aligned with FDA, ICH, and EU Annex 1 regulatory requirements and company objectives.

Essential Functions

Reasonable accommodations will be made to enable individuals with disabilities to perform the essential functions.

* Provide end-to-end leadership and accountability for commercial DS manufacturing operations, including upstream, downstream, central services, equipment and component preparation, and execution of the site master production schedule.

* Own delivery of commercial supply commitments by proactively managing capacity, supply risk, operational readiness, and execution discipline in a GMP environment.

* Ensure manufacturing operations are executed in full compliance with FDA, ICH, EU Annex 1, environmental health and safety (EHS), and internal quality system requirements; serve as the accountable manufacturing leader during regulatory inspections and audits.

* Define and execute the manufacturing operating strategy aligned with site and enterprise objectives, including lifecycle management, process robustness, and long-term capacity planning for commercial operations.

* Partner closely with Quality, Supply Chain, MSAT, Engineering, Automation, and Facilities to ensure reliable operations, effective deviation management, change control, validation, and sustained state of control.

* Lead manufacturing scheduling and coordination of materials, equipment, and staffing to optimize throughput, right-first-time performance, and operational efficiency.

* Establish and manage manufacturing performance systems, including safety, quality, delivery, cost, and people metrics, drive accountability through tiered management and visual performance management.

* Own the manufacturing operating budget (OPEX) and capital plan (CAPEX); ensure disciplined financial management and delivery of productivity and cost improvement commitments.

* Build, lead, and develop a high-performing manufacturing leadership team; drive capability development, succession planning, and talent retention.

* Champion continuous improvement initiatives to improve robustness, yield, equipment reliability, and cost of goods (COGS) in a commercial manufacturing environment.

* Represent the Canton site manufacturing organization in internal governance forums, network initiatives, due diligence activities, and external stakeholder engagements as required.

The above statements are intended to describe the nature of work performed by those in this job and are not an exhaustive list of all duties. Nothing in this job description restricts management's right to assign or reassign duties and responsibilities to this job at any time which reflects management's assignment of essential functions.

Minimum Education , Experience & Skills

* Bachelor's degree in engineering, biological sciences, chemistry, or a related technical discipline required; advanced degree (MS, PhD) or MBA strongly preferred.

* Minimum of 12-15 years of progressive leadership experience in pharmaceutical or biotechnology manufacturing, with substantial experience in commercial vaccine or biologics drug substance operations.

* Demonstrated end-to-end operational leadership across upstream and downstream processing, buffer/solution preparation, equipment preparation, and GMP manufacturing scheduling.

* Extensive experience leading organizations through FDA inspections and operating in compliance with FDA, ICH, and EU Annex 1 requirements for sterile and biologics manufacturing.

* Strong business and financial acumen, including management of large operating budgets, capital investment planning, and cost reduction initiatives.

* Proven track record of building inspection-ready organizations with strong quality culture and disciplined execution.

* Expertise in operational excellence methodologies (Lean, Six Sigma, TPM) and the application of KPIs and data analytics to drive sustained performance improvement.

* Exceptional leadership, communication, and influencing skills with the ability to operate effectively in a matrixed, performance-driven manufacturing environment.

* Experience with manufacturing execution systems (MES), ERP…