More jobs:
Research Associate I/Research Associate II, Manufacturing Process Research
Job in
Carlsbad, San Diego County, California, 92002, USA
Listed on 2026-08-30
Listing for:
Scorpion Therapeutics
Full Time
position Listed on 2026-08-30
Job specializations:
-
Research/Development
Research Scientist, Research Assistant/Associate, Pharmaceutical Science/ Research, Biotechnology
Job Description & How to Apply Below
Position:
Research Associate I / Research Associate II, Manufacturing Process Research
Work Location:
Carlsbad, CA
- Execute defined laboratory experiments supporting oligonucleotide process development and manufacturing research.
- Perform laboratory-scale solid-phase synthesis and related operations (e.g., coupling, oxidation, detritylation, deprotection, cleavage).
- Prepare, process, and purify oligonucleotide materials (e.g., chromatography, filtration, tangential flow filtration, annealing, concentration, isolation).
- Support process-development programs across modalities (e.g., antisense, siRNA, conjugated, modified oligonucleotides).
- Evaluate process conditions, materials/resins/reagents, and equipment settings under guidance.
- Prepare drug substance, intermediates, research materials, impurity samples, and analytical/manufacturing support samples.
- Collect/review experimental and analytical data; record results in electronic lab notebooks.
- Contribute to technical documents (reports, presentations, process summaries) under review.
- Operate lab equipment after training; maintain safety, data integrity, and organized lab operations.
- Support investigations into unexpected results; collaborate with cross-functional partners.
- Bachelor’s degree in a relevant scientific field;
Research Associate II requires at least 2 years relevant experience. - Understanding of basic chemistry/lab practices and problem solving.
- Ability to follow procedures and maintain accurate records; communicate results.
- Attention to detail, strong communication skills, cross-functional collaboration.
- Ability to stand for extended periods; safe work with hazardous chemicals/biological/pharmaceutical materials; occasional schedule flexibility.
- Experience with oligonucleotides/nucleic acids/peptide conjugates or process chemistry/purification/pharma manufacturing.
- Familiarity with solid-phase synthesis, chromatography, filtration, tangential flow filtration, and/or lab-scale manufacturing.
- Exposure to HPLC, LC-MS, UV detection; use of ELN/LIMS/spreadsheets.
- Knowledge of GLP/GMP, chemical hygiene, data integrity; experience preparing technical reports/presentations.
Position Requirements
10+ Years
work experience
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