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Senior Manager, Manufacturing Sciences – Technology

Job in Cary, Wake County, North Carolina, 27518, USA
Listing for: Jobtailor
Full Time position
Listed on 2026-07-23
Job specializations:
  • Quality Assurance - QA/QC
    Regulatory Compliance Specialist, Quality Engineering
  • Pharmaceutical
    Regulatory Compliance Specialist, Quality Engineering
Salary/Wage Range or Industry Benchmark: 180000 - 240000 USD Yearly USD 180000.00 240000.00 YEAR
Job Description & How to Apply Below

Responsibilities

  • Serve as the MS&T Product Lead for the commercial small molecule product throughout its lifecycle
  • Develop and execute manufacturing science strategies supporting a high-volume commercial program
  • Provide advanced technical leadership supporting commercial manufacturing campaigns
  • Drive continuous improvement initiatives focused on process capability, manufacturing reliability, product quality, and operational efficiency
  • Lead execution of process validation and PPQ studies for new scales and suites
  • Own CPV strategy, execution, and data trending across the commercial program
  • Lead manufacturing investigations, deviations, CAPAs, and change controls
  • Collaborate with Quality Assurance and Quality Control to ensure compliance and performance
  • Manage supplier technical performance through governance meetings and business reviews
  • Author technical content of regulatory submissions supporting global filings
Requirements
  • Bachelor's degree in Engineering, Pharmaceutical Sciences, Chemistry, Chemical Engineering, Biology, or related scientific discipline
  • Advanced degree (MS, PhD, or MBA) strongly preferred
  • 10+ years of progressively responsible pharmaceutical or biotechnology manufacturing experience
  • Demonstrated experience in technology transfer, process validation, CPV, lifecycle management, manufacturing investigations, and change controls
  • Experience with film-coated, modified-release solid oral dosage forms and associated dissolution testing strongly preferred
  • Experience supporting a high-volume commercial manufacturing program, including parallel scale-up or new suite qualification activities
  • Experience supporting regulatory inspections and global regulatory submissions
  • Demonstrated ability to mentor and develop junior technical staff within a global manufacturing organization and contract manufacturing network
Core Competencies

Demonstrates expertise in manufacturing science strategies, process validation, and continuous improvement initiatives within a high-volume commercial pharmaceutical environment. Proven ability to lead technical investigations, manage compliance, and mentor junior staff in a global manufacturing context.

Highest-signal resume keywords
  • Manufacturing Science Strategies
  • Process Validation
  • Continuous Improvement Initiatives
  • Regulatory Submissions
  • Technology Transfer
Hard Skills
  • Process Validation
  • CPV
  • Lifecycle Management
  • Manufacturing Investigations
  • Change Controls
  • Dissolution Testing
  • High-Volume Commercial Manufacturing
  • Film-Coated Dosage Forms
  • Modified-Release Dosage Forms
  • Supplier Technical Performance Management
Soft Skills
  • Mentoring
  • Collaboration
  • Leadership
Certifications & Qualifications
  • Bachelor's Degree in Engineering
  • Pharmaceutical Sciences
  • Chemistry
  • Chemical Engineering
  • Biology
  • Advanced Degree (MS, PhD, or MBA)
Industry Keywords
  • Pharmaceutical Manufacturing
  • Biotechnology
  • Regulatory Compliance
  • Quality Assurance
  • Quality Control
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Position Requirements
10+ Years work experience
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