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Research Chemist - Organic Synthesis

Job in Centurion, 0014, South Africa
Listing for: Placements24
Full Time position
Listed on 2026-09-21
Job specializations:
  • Science
    Drug Discovery, Pharmaceutical Science/ Research, Research Scientist, Biotechnology
  • Research/Development
    Drug Discovery, Pharmaceutical Science/ Research, Research Scientist, Biotechnology
Job Description & How to Apply Below

About the Role

Our client is actively seeking a highly skilled and creative Research Chemist specializing in Organic Synthesis to join their innovative R&D team in Centurion . This role is critical for the design and execution of complex synthetic routes to novel compounds with potential pharmaceutical applications. You will be a key contributor to our discovery pipeline, working in a state-of-the-art laboratory environment that encourages scientific rigor and exploration.

This is an excellent opportunity for a chemist who is passionate about drug discovery, thrives in a fast-paced environment, and is eager to make significant contributions to the development of new therapeutic agents, fostering a culture of innovation and scientific excellence.

Key Responsibilities
  • Design and execute multi-step synthetic routes for complex organic molecules, intermediates, and active pharmaceutical ingredients (APIs).
  • Optimize reaction conditions to improve yield, purity, and scalability of synthetic processes.
  • Utilize a wide range of modern synthetic organic chemistry techniques and instrumentation.
  • Characterize synthesized compounds using spectroscopic methods (e.g., NMR, Mass Spectrometry, IR) and chromatographic techniques (e.g., HPLC, GC).
  • Collaborate closely with medicinal chemists, process chemists, and analytical chemists to advance drug discovery projects.
  • Troubleshoot synthetic challenges and proactively identify solutions to overcome obstacles.
  • Maintain detailed and accurate laboratory records in compliance with company standards.
Requirements
  • Ph.D. in Organic Chemistry or a closely related field.
  • Minimum of 4 years of post-doctoral or industrial experience in synthetic organic chemistry.
  • Proven track record in designing and executing complex total syntheses of natural products or pharmaceuticals.
  • Strong knowledge of reaction mechanisms, stereo chemistry, and retrosynthetic analysis.
  • Proficiency in spectroscopic and chromatographic techniques for compound characterization.
  • Excellent problem-solving abilities and a keen attention to detail.
  • Strong written and oral communication skills, including the ability to present research findings effectively.
Benefits
  • Competitive salary and comprehensive benefits package, including health and retirement plans.
  • Opportunities for professional growth, attending scientific conferences, and continuous learning.
  • Access to cutting-edge research facilities and advanced synthetic equipment.
  • A dynamic and collaborative work environment in Centurion focused on scientific innovation.
  • Support for work-life balance with flexible working arrangements where possible.
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