Senior Process Engineer / SME – Chromatography Systems
Job in
Champaign, Champaign County, Illinois, 61825, USA
Listed on 2026-08-01
Listing for:
United Consulting Hub
Full Time
position Listed on 2026-08-01
Job specializations:
-
Pharmaceutical
Pharmaceutical Science/ Research, Validation Engineer, Pharmaceutical Manufacturing
Job Description & How to Apply Below
The Chromatography SME will provide technical leadership for chromatography systems supporting large-scale purification operations. This role requires extensive hands-on experience with chromatography equipment, resin handling, column packing, buffer preparation, and continuous purification technologies, including Simulated Moving Bed (SMB) chromatography.
This individual will serve as the primary technical expert for chromatography equipment and purification operations throughout startup, operational readiness, troubleshooting, and project execution activities.
Key Responsibilities- Serve as technical SME for chromatography systems and purification equipment
- Support startup, commissioning, qualification, and operational readiness
- Provide vendor oversight and challenge technical solutions when required
- Troubleshoot equipment and process issues
- Support equipment acceptance and performance verification activities
- Simulated Moving Bed (SMB) Chromatography
- Column Packing and Unpacking
- Column Operation
- Purification System Troubleshooting
- BS in Chemical Engineering, Biochemical Engineering, Biotechnology, or related field.
- 8+ years of chromatography or downstream processing experience
- Extensive experience with chromatography systems
- Column packing
- Buffer preparation
- Strong understanding of purification equipment and mechanical systems
- Experience managing equipment vendors and suppliers
- SMB chromatography experience
- Experience with mAb, plasma, biologics, nutraceutical, or protein processing
- Experience with Cytiva, Pall, Novasep, or equivalent chromatography platforms
Position Requirements
10+ Years
work experience
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