UNIV - Post Doctoral Scholar - Pediatrics: DCRI

Job Description Summary

Department of Pediatrics, Darby Children’s Research Institute’s Laboratory of Dr. Haemmerich is seeking a Post‑Doctoral researcher to assist ongoing research efforts to develop targeted chemotherapy delivery for cancer treatment.

A doctoral degree (PhD or MD/PhD) in a discipline related to biology, bioengineering, or biomedicine.

• 25% Perform and/or assist in therapeutic rodent studies, including intravenous administration of liposomal chemotherapy, blood sampling, and animal imaging.
• 25% Assist and/or perform computer modeling studies of tumor drug delivery.
• 10% Produce and characterize liposomal drug carriers, formulating the liposomes and measuring release characteristics and size.
• 10% Prepare and maintain primary cancer cell cultures, including standard cell culture methods and, in some cases, cell viability analyses with in‑vitro efficacy studies.
• 10% Perform routine laboratory experiments, review and analyze data, and prepare protocols and reports.
• 10% Maintain, clear, complete, and up‑to‑date lab notebooks and documentation of all experiments, results, and reports, including organization of results in spreadsheets and other documents.
• 5% Process and analyze tissues such as rodent tumors, quantifying tumor drug uptake with established methods such as fluorometry and/or high‑performance liquid chromatography (HPLC).
• 5% Assist in animal surgeries, including surgical removal of tumors and implantation of vascular catheters.

Ability to perform job functions in an upright position (continuous). Ability to perform job functions in a seated position (continuous). Ability to perform job functions while walking/mobile (frequent). Ability to climb stairs (infrequent). Ability to work indoors (continuous). Ability to work in all cold temperature extremes, i.e., spot coolers (frequent). Ability to bend at the waist (frequent). Ability to twist at the waist (frequent).

Ability to perform 'pinching' operations (continuous). Ability to fully use both hands/arms (continuous). Ability to perform repetitive motions with hands/wrists/elbows and shoulders (continuous). Ability to fully use both legs (continuous). Ability to reach in all directions (continuous). Possess good finger dexterity (continuous). Ability to maintain tactile sensory functions (continuous). Ability to maintain good olfactory sensory function (continuous). Ability to lift and carry 15 lbs.,

unassisted (frequent). Ability to lift objects, up to 15 lbs., from floor level to a height of 72 inches, unassisted (frequent). Ability to lower objects, up to 15 lbs., from a height of 72 inches to floor level, unassisted (frequent). Ability to push/pull objects, up to 15 lbs., unassisted (infrequent). Ability to lift and carry objects up to 15 lbs.

a distance of five floors and to outlying buildings (frequent). Ability to maintain 20/40 vision, corrected (continuous). Ability to see and recognize objects close at hand (continuous). Ability to see and recognize objects at a distance (continuous). Ability to match or discriminate between colors (continuous). Ability to determine distance/relationship between objects; depth perception (continuous). Good peripheral vision capabilities (continuous). Ability to maintain hearing acuity, with correction (continuous).

Ability to perform gross motor functions with frequent fine motor movements (continuous). Qualified physically for respirator use, initially and annually. Ability to work alone in isolated areas, such as darkrooms (frequent). Ability to obtain and maintain a valid driver’s license. Computer literacy. Ability to work rotating shifts as required. Ability to work overtime as required. Ability to learn and use new processes, tools and equipment as required.

Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need.

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