UNIV - Research Specialist II - Department of Biochemistry

Job Description Summary

The Department of Biochemistry & Molecular Biology at the Medical University of South Carolina (MUSC) invites applications for a Research Specialist II position in the laboratory of Dr. Huimin Zhang, who joined MUSC as an Assistant Professor in November 2025. This position is available immediately and offers an exciting opportunity to participate in cutting‑edge cancer and genome stability research within a highly collaborative academic environment.

The Zhang Laboratory is dedicated to understanding the molecular mechanisms that drive genomic instability in cancer and to identifying therapeutic vulnerabilities that can be leveraged to improve cancer treatment. Current research focuses on DNA damage response and repair pathways, with particular emphasis on how cells respond to chemotherapy‑induced DNA damage and maintain genome integrity. Ongoing projects investigate the mechanisms of action and cellular responses to topoisomerase‑targeting agents, with the goal of developing more effective and selective cancer therapies.

Medical University of South Carolina (MUSC - Univ)

Employee

Research Grant

CC000954 COM BIOCHEM Operations CC

Hourly

University-GEN
08

45,300.

- 77,000.000

40

The Research Specialist will work closely with the principal investigator and other laboratory members to conduct molecular and cellular biology experiments, perform mammalian cell culture, analyze and interpret experimental data, and assist in the preparation of research reports and presentations. The successful candidate will contribute to ongoing research projects and support the overall operation of the laboratory in a collaborative team environment.

The Research Specialist will work closely with the principal investigator and other laboratory members to conduct molecular and cellular biology experiments, perform mammalian cell culture, analyze and interpret experimental data, and assist in the preparation of research reports and presentations. The successful candidate will contribute to ongoing research projects and support the overall operation of the laboratory in a collaborative team environment.

• Required to have a minimum Bachelor’s degree in Biology or related subjects.
• Hands-on laboratory experience in molecular and cellular biology techniques, such as PCR, cloning, Western blotting, mammalian cell culture, and microscopy.
• Master’s degree or equivalent research experience.
• Strong organizational, written, and oral communication skills.
• Ability to work both independently and collaboratively within a research team.
• The position will remain open until filled.

Must be able to work with little or no supervision.

• Work collaboratively with the principal investigator and laboratory members to design and execute research experiments.
• Perform molecular biology techniques, including PCR, DNA cloning, Western blotting, nucleic acid purification, and related assays.
• Conduct microscopy, functional assays, and other experimental procedures to support ongoing research projects.
• Accurately document experimental procedures, analyze data, and maintain detailed laboratory records.

• Maintain, expand, and characterize mammalian cell lines under sterile culture conditions.
• Perform cell-based assays, drug treatments, genetic manipulations, and other experimental procedures as required.
• Assist in the development and optimization of new experimental protocols.

• Assist with laboratory organization, inventory management, and procurement of research supplies.
• Prepare purchase requests, monitor orders, and maintain adequate stocks of laboratory reagents and consumables.
• Coordinate experimental schedules and facilitate communication among laboratory personnel and collaborators.

• Operate, calibrate, and maintain…