Facilities Engineer II

Company Overview

Afton Scientific is a privately held, PE-backed sterile fill‑finish contract development and manufacturing organization (CDMO) headquartered in Charlottesville, Virginia. For over 20 years, Afton has provided aseptic manufacturing services for biologics and small‑molecule injectables, supporting clients from clinical trials through commercial supply. The company operates FDA‑inspected, cGMP‑compliant manufacturing facilities and is currently executing a $200M+ expansion (Avon IV) that will add high‑speed isolator‑based filling lines and significantly increase capacity.

Afton serves pharmaceutical and biotech companies across oncology, metabolic/obesity therapeutics, immunology, infectious disease, and rare disease markets. Our location in central Virginia places us within a one‑day drive of approximately 50% of the U.S. population, a strategic advantage for cold‑chain and time‑sensitive pharmaceutical logistics.

• Provide technical expertise to production teams, resolving issues as they arise and collaborating closely with Engineering and other support functions.
• Support daily production operations within the manufacturing area and serve as the first responder for equipment malfunctions.
• Partner with Facilities Department to maintain appropriate inventory levels of critical spare components and develop/update preventive maintenance (PM) instructions for production equipment.
• Assist in coordinating and executing calibration and preventive maintenance activities.
• Complete all required documentation including work orders and GMP records accurately, clearly, and on time.
• Troubleshoot equipment issues, working with equipment owners, engineers, and external vendors to drive timely resolution.
• Proactively engage with support teams to develop solutions for recurring or emerging equipment challenges.
• Foster strong working relationships within the Facilities team and with internal and external customer departments.
• Collaborate with Manufacturing, Operations, Environmental Health & Safety, and other cross‑functional groups to meet production goals.
• Support onboarding and technical training of Manufacturing personnel on process equipment.
• Assist MST team with new product introductions and technology transfer activities.
• Support the revision and management of manufacturing documents such as Batch Records and SOPs.
• Adapt quickly to changes in production schedules and reprioritize tasks to minimize operational disruptions.

Participate in periodic on‑call rotations to monitor and respond to equipment issues.

• High school diploma with at least six (6) years of experience performing maintenance on manufacturing equipment, or an associate’s degree or higher in Pharmaceutical Sciences, Engineering, or a related field (preferred).
• Experience working in sterile fill and finish manufacturing environments.
• Strong understanding of GMP standards, regulatory requirements, and industry best practices.
• Ability to work independently while following established procedures, guidelines, and operational practices.
• Background in continuous process improvement.
• Strong communication and collaboration skills, with a commitment to maintaining high‑quality standards.

• Understanding of high‑speed aseptic filling operations and isolator barrier system technologies.
• Experience working with single‑use components used in drug product formulation, sterile filtration, and aseptic filling processes.
• Proficiency in Microsoft Office Suite.
• Proficiency with Computerized Maintenance Management Systems (CMMS).

• The employee is regularly required to speak or hear.
• The employee must frequently use their hands or fingers to handle, feel, or control objects, tools, or controls.
• The employee is occasionally required to stand, walk, sit, and reach with hands and arms.
• The employee must occasionally lift and/or move up to 50 pounds.
• The noise level in the work environment is usually low to moderate.
• Require extended computer use and data analysis.
• Must complete required onboarding training, including company policies and procedures, data integrity and confidentiality expectations,…