Research Associate in Biochemistry & Molecular Genetics

Overview

The Kaya Lab at UVA is seeking a highly motivated postdoctoral researcher to join our dynamic and collaborative team focused on both basic and translational research into the biology of aging and age‑related diseases. The lab utilizes a range of experimental systems, including transgenic animal models, dietary interventions, and cutting‑edge genome engineering tools.

• Neuroinflammation in Neurodegenerative Diseases – investigate the role and molecular regulators of neuroinflammation in mouse models of neurodegeneration.
• Cellular Senescence and Polyploidy – understand how polyploid genomes influence senescence and the associated cellular phenotypes.
• Aging, Cancer, and Metabolism – explore the mechanisms of age‑ and cancer‑associated metabolic disorders and epigenetic changes linked to aneuploidy.
• Mitochondrial DNA in Aging and Disease – study the role of cytoplasmic mitochondrial DNA fragments in aging and neurodegeneration.

The lab highly encourages candidates to propose independent projects that align with its overarching research goals.

• Design and execute experiments, including molecular and cellular assays, animal work, and data analysis.
• Prepare manuscripts and grant applications, and present findings at lab meetings and conferences.
• Supervised by a senior scholar, expect to publish results of research during the training period.
• Continuous development of a full‑time academic or research career; additional duties may be assigned.

Education:

Applicants must have a doctoral degree (Ph.D. in neuroscience, mitochondrial biology, cancer biology, aging, or a related field) in hand by the start date.

• Mammalian cell culture experience.
• Mouse genetics and animal husbandry experience.
• Proficiency in molecular cloning and CRISPR or other genome‑engineering techniques.
• Experience in tissue preparation for immunohistochemistry/immunofluorescence.

Candidates should be self‑motivated, able to work independently and collaboratively, and possess strong analytical, organizational, and communication skills.

This is a 12‑month appointment with the possibility of renewal for up to two additional one‑year increments, contingent upon satisfactory performance and available funding. Salary will be commensurate with education and experience. The position is exempt‑level and includes university benefits.

This position is based in Charlottesville, VA, and must be performed fully on‑site.

Background checks and pre‑employment health screenings will be conducted on all new hires prior to employment.

The University of Virginia is an equal opportunity employer. All interested persons, including veterans and individuals with disabilities, are encouraged to apply. Learn more about UVA’s commitment to non‑discrimination and equal opportunity employment.