Postdoctoral Research Associate, Division of Pulmonary and Critical Care Medicine

The Department of Medicine at the University of Virginia is seeking a Postdoctoral Research Associate to work in the laboratory of Dr. Jeffrey Sturek, MD, PhD. The Sturek Laboratory is an exciting NIH-funded group which focuses on translational pulmonary immunology and fibrosis. The laboratory utilizes both human and patient samples to explore disease phenotypes and associations as well as murine and in vitro model systems to test novel biological mechanisms.

Techniques of interest focus around high-dimensional immunophenotyping via mass cytometry and spectral flow cytometry, immunofluorescence and imaging mass cytometry, and RNA sequencing. Disease areas of interest are fibrotic lung diseases such as idiopathic pulmonary fibrosis, pulmonary graft-vs-host disease, acute respiratory distress syndrome, and respiratory infections.

The successful candidate will serve as a leader of laboratory projects, provide scientific and technical guidance on experimental design, conduct and interpretation, and also perform studies needed to advance the missions of our research program. This is a leadership position within the lab, and the successful candidate will serve as the principal investigator's scientific partner. They should possess strong organizational skills to enable the administrative, regulatory, and operational needs of the lab, and they should be willing and eager to learn new techniques to bring to the lab.

They will be expected to help teach other trainees rotating in the laboratory, including pulmonary and critical care fellows, medicine residents, PhD candidates, medical students, and undergraduates. They should also possess excellent verbal and written communication skills to facilitate our training mission and to contribute to preparation of research proposals and manuscripts. The candidate may submit for individual postdoctoral research fellowship funding if consistent with their career goals.

The specific focus of projects for this posting are related to the role of B cells and IgA in idiopathic pulmonary fibrosis, and are supported by a recently awarded NIH R01.

Postdoctoral employment is temporary and is normally limited to an individual who has been awarded a Ph.D. or equivalent doctorate within the previous five years and who will be involved in full-time research or scholarship at the University. Employment as a Postdoctoral Research Associate is viewed as training and is preparatory for a full-time academic or research career, is supervised by a senior scholar, and allows the appointee to publish the results of his/her research or scholarship during the training period.

The position is a 12-month appointment with the possibility of renewal contingent upon satisfactory performance and the availability of funding.

Minimum Qualifications:

Education:

PhD in the Biosciences or an MD with a research emphasis is required at the time of hire

Preferred Experience:

The ideal candidate will have demonstrated experience with either mouse models of pulmonary disease, or murine or human immunology, flow cytometry and histology.

Experience with primary cell culture, functional analyses in vitro and in vivo and characterization of the molecular features of cells (DNA/RNA/Protein) is essential. Likewise, experience with retro- and lenti-viral production and transduction, RNAi-based strategies for post-transcriptional regulation of gene expression and CRISPR/Cas9 techniques are desired. Additionally, experience with or interest in modern techniques in high-dimensional data analysis such as mass cytometry, spectral flow, and RNAseq is strongly preferred.

Physical Demands

This is primarily a sedentary job involving extensive use of desktop computers. The job does occasionally require traveling some distance to attend meetings, and programs.

This is an exempt-level, benefited position. For more information on the benefits available to postdoctoral associates at UVA, visit postdoc.virginia.edu and hr.virginia.edu/benefits.

This position is based in Charlottesville, VA, and must be performed fully on-site.

To learn more about UVA and the Charlottesville area, visit UVA Life and Embark CVA.

Background checks and pre-employment health screenings will be conducted on all new hires prior to employment.

How to Apply

Please apply online, by searching for requisition number R0078174. Complete an application with the following documents:

* Resume

* Cover Letter

Upload all materials into the resume submission field. You can submit multiple documents into this one field or combine them into one PDF. Applications without all required documents will not receive full consideration.

Internal applicants:
Search and apply for jobs on the UVA Internal Careers website.

Reference checks will be completed by UVA's third-party partner, Skill Survey, during the final phase of the interview. Five references will be requested, with at least three responses required.

For questions about the application process, please contact Jessica Russo, Senior Recruiter,…