Senior Scientist

The W.M. Keck Biomedical Mass Spectrometry Lab – a part of the Biomolecular Analysis Facility Core at the University of Virginia – seeks a Senior Scientist to expand our work in the areas of proteomics and metabolomics using state‑of‑the‑art instruments to support research within the institution in areas such as basic science research, the Cancer Center, and clinical projects. This position requires expertise and hands‑on experience in biomedical science.

The candidate should have documented expertise in mass spectrometry and chromatography as well as protein and small molecule chemistry. You will support the director through sample preparation, operation/maintenance of advanced mass spectrometers (Orbitrap ‑X – Vanquish Neo and Orbitrap Astral Zoom – Evosep Enzo), and data analysis using advanced software packages (Proteome Discoverer, Compound Discoverer, Scaffold, etc). This work will advance institutional goals in proteomic and metabolomic profiling and translational research.

The ideal candidate will have a proven record of excellent communication and team support. You should be highly motivated and able to work independently when designing and executing experiments. The customer support of researchers within the institution is a high priority. Projects will include use of existing techniques to answer current biological challenges and the development of new technologies in proteomics and metabolomics.

• Doctoral degree, preferably a Ph.D. in Mass Spectrometry or a closely related field.
• Prior experience in qualitative and quantitative proteomics and metabolomics technology and nano‑liquid chromatography and mass spectrometry (LC‑MS; on Orbitrap Fusion, Orbitrap Astral, and/or Orbitrap ‑X).
• Familiarity with the entire metabolomics and/or proteomics pipeline (including sample preparation, LC and MS operation, and data analysis) and ability to conduct independent projects.
• Experience managing multiple projects across multiple laboratories.
• Demonstrated scientific productivity with excellent written and oral communication skills.
• Attention to detail, ability to learn new technologies, flexibility, and time management.
• 5+ years of direct experience in mass spectrometry or a closely related field and 10+ years in proteomics or metabolomics.
• Collaboration across multiple disciplines and ability to engage investigators in project design, execution, and data analysis.
• Experience in publication and grant writing.
  
  Experience with Proteome/Compound Discoverer, Scaffold, MS Dial, Metabo Analyst, etc.
• Advanced knowledge of Thermo mass spectrometers – operation and maintenance.

This is primarily a sedentary job involving extensive use of desktop computers. The position occasionally requires traveling some distance to attend meetings.

Salary will be commensurate with education and experience. This is an exempt‑level, benefited position.

Initial appointments and reappointments may be made in increments of one to three years, contingent upon satisfactory performance and the availability of funding.

This position is based in Charlottesville, VA, and must be performed fully on‑site.

Background checks and pre‑employment health screenings will be conducted on all new hires prior to employment.

Equal Opportunity Statement:
The University of Virginia is an equal opportunity employer. All interested persons are encouraged to apply, including veterans and individuals with disabilities. Learn more about UVA’s commitment to non‑discrimination and equal opportunity employment.