Bioinformatics Full-Stack Developer

Position Purpose

The bioinformatics full-stack developer is responsible for building and maintaining a digital bridge between frontend user-facing applications and backend bioinformatics pipelines. This position will oversee the delivery of high-quality software capable of analyzing nucleotide sequence data to produce actionable and user-friendly reports. The ideal candidate will be prepared to oversee and contribute to the development of an integrated software stack for characterization of DNA sequencing data on local hardware systems.

This position is a full-time, on-site role at the Signature Science office in Charlottesville, VA.

• Work with a team to develop and test full-stack software for analysis and interpretation of whole genome sequencing data, including front and back-end software components.
• Implement and test data processing workflows and automated analysis pipelines. Optimize reproducible software pipelines that produce consistent, standardized results.
• Oversee workflow bench marking and testing, identifying inconsistencies and resolving issues.
• Contribute to management of computing hardware, operational logistics, and data warehousing.
• Contribute to the preparation of standard operating procedures, document source code/workflows, and write reports to summarize computational requirements, processing status, and customized analysis results.
• Communicate and interact regularly with project team members and stakeholders.

• Advanced proficiency working in a Unix/Linux environment.
• Advanced proficiency using version control software (e.g., Git) to manage programming code.
• Advanced proficiency with C++.
• Proficiency in developing software user interfaces.
• Proficiency with open-source software, tools, and databases for analyzing next-generation sequencing data.
• Proficiency with at least one programming or run-time interpreted programming language.
• Proficiency with Continuous Integration and Continuous Deployment/Delivery (CI/CD).
• Experience managing a development project including multiple teams.
• Familiarity with issue and project tracking software.
• Skilled at time and priority management.
• Excellent written and oral communication skills.
• Preferred:
  Proficiency with Python.
• Preferred: proficiency with R, RMarkdown, and the "tidyverse" tools for data analysis.
• Preferred:
  Experience with Next Flow, Snake Make, or similar workflow/pipeline management systems.
• Preferred:
  Proficiency working with and developing using containerization technology.
• Preferred:
  Familiarity with AWS and/or Azure cloud computing.

• Required:
  
  5+ years of previous work experience in a full-stack developer role.
• Required:
  
  BS/BA in Computer Science, Software Engineering, Bioinformatics, or related field.
• Preferred: MS or PhD in Computer Science, Software Engineering, Bioinformatics, or related field.
• Preferred:
  Experience managing and analyzing large-scale datasets produced by DNA sequencing platforms and delivering solutions for managing, visualizing, analyzing, and interpreting genomic data.

• This position requires that the candidate be willing and able to complete a successful background screening for a security clearance. Candidates with a current security clearance will receive preference.

• Serve as a task leader within one or more projects.

• Ability to work in varying conditions to include traditional office environments with extended sedentary periods required for code development and testing.