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Senior Mechanical Engineer

Job in Chicago, Cook County, Illinois, 60290, USA
Listing for: BiomeSense
Full Time position
Listed on 2026-10-17
Job specializations:
  • Engineering
    Hardware Engineer, Mechanical Engineer, Test Engineer, Manufacturing Engineer
Salary/Wage Range or Industry Benchmark: 100000 - 125000 USD Yearly USD 100000.00 125000.00 YEAR
Job Description & How to Apply Below
Senior Mechanical Engineer

Compensation: $100k – $125k salary + 0.1%– 0.2% equity + benefits

Full benefits, including health coverage, PTO & parental leave

About Biome Sense

Biome Sense is a life sciences startup applying gut microbiome technologies (Gut Lab, Meta Biome) to advance personalized medicine. We partner with UCSF, UCSD, NIH & the University of Chicago & are backed by Lab Corp Ventures, Bluestein Ventures, Seerave Foundation & Emil Capital Partners.

Key Responsibilities

You will own key technical work streams responsible for the success of our next-generation Gut Lab hardware, while providing hands‑on support.

  • Mechanical Design of Novel Hardware:
    Devise elegant solutions to complex mechanical design problems, balancing performance, risk, and timelines
  • Systems Integration:
    Integrate mechanical, electrical, and fluidic systems into robust products; resolve system-level tradeoffs
  • Hardware Build & Test:
    Perform detailed electrical, mechanical, and fluidic assembly of prototypes and sub-assemblies; lead hands‑on validation of new designs
  • Troubleshooting & Repair:
    Diagnose and repair complex hardware, software, and firmware issues in lab and field; identify root causes and drive fixes
  • Testing & Automation:
    Design and improve test setups, fixtures, and automation to optimize assembly and validate hardware; maintain a clean, organized, inventoried hardware lab
  • Documentation & Quality:
    Create clear SOPs, manuals, test records, and design documentation for repeatable production; flag risks and assembly feedback early
Qualifications
  • Bachelor’s Degree in Engineering or related field and 5+ years in hardware development
  • Experience independently designing complex, novel hardware and test fixtures using CAD
  • Proven ability and willingness to perform precise, hands‑on assembly and testing of complex electromechanical hardware
  • Experience with prototyping techniques (e.g., 3D printing, light machining)
  • Proven ability to perform detailed wiring, harnessing, and soldering
  • Highly organized, proactive, and independent; owns ambiguous work through resolution and collaborates across disciplines
  • Experience with instrument control software and scripting; able to interpret test results and translate findings into design improvements
Preferred Qualifications:
  • Experience taking a new product from prototype to production
  • Expertise in Design for Assembly (DFA) and Design for Manufacturing
Position Requirements
10+ Years work experience
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