Senior Director, Research Strategy and Operations; Core Team Leader

Position: Senior Director, Research Strategy and Operations (Core Team Leader)
Passionate about precision medicine and advancing the healthcare industry?

Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.

We are seeking an industry veteran to serve as the Core Team Leader (CTL) to support our growing product  this high-impact role, you will act as the “Leader of the Product Development Lifecycle." You will move beyond simple project coordination to assume full accountability for the execution and commercial launch of complex regulated diagnostic products. You will lead a cross-functional Core Team - comprising leaders from R&D, Clinical, Regulatory, Quality, Software, and Operations - to navigate the journey from concept to commercialization.

This is a matrix leadership role. You will partner with a Product Manager (who defines market strategy) and a Project Manager (who manages tactical schedules), while you provide the strategic glue, operational oversight, and decision-making authority required to deliver the product to market.

This means real-time escalation and attribution of root causes when projects are trending off-track, inputs/expectations are not clear, and resources are not appropriately allocated to the work. CTLs are responsible for getting what they need from other teams to achieve the overall project objective and timeline, and speaking up loudly if that’s not happening.

Key Responsibilities Cross-Functional Leadership & Accountability Serve as the single point of accountability for the development lifecycle, ensuring the team delivers against the Target Product Profile (TPP) and Product Requirements against a defined timeline.

Lead a dedicated Core Team of functional heads (Science, Engineering, Quality, Regulatory, Lab Ops) without direct line authority. You must effectively negotiate priorities, drive consensus among peers with competing incentives, and align disparate groups toward a shared vision.

Ensure the technical and clinical vision defined at the start of the project is consistently understood and executed across all technical sub-teams, preventing scope creep or strategic drift.

Proactively identify and resolve friction between functional groups (e.g., Commercial timelines vs. R&D feasibility). You will serve as the primary mediator, fostering constructive debate to reach rapid, data-driven decisions without needing constant escalation.

Stage-Gate Governance & Strategic Execution Lead the product team through formal Stage-Gate Reviews (Phase Exits). You must possess the executive presence to synthesize complex technical, clinical, and operational data into clear, actionable business narratives for the leadership team.

Proactively identify critical path risks. You will drive difficult trade-off decisions between scope, timeline, and resources, escalating structural blockers to the Executive Leadership Team only when necessary.

Collaborate with functional leadership to ensure appropriate resource allocation, ensuring the project aligns with the broader Tempus portfolio priorities.

Design Control & Operational Scale Champion a development process compliant with Design Control (21 CFR 820) and ISO 13485 standards. You will guide the team through the rigors of LDT, 510(k), or PMA regulatory pathways.

Oversee the critical transition from R&D to Clinical Lab Operations. You will ensure the "order-to-result" workflow is robust, scalable, and ready for commercial volume prior to launch.

Act as the primary link between technical development and…