Clinical Research Nurse - Cancer Center

Clinical Research Nurse 1 - Cancer Center-23694

Location: Chicago, Illinois

Work Type: Full Time (Total FTE 1.0)

Shift: Shift 1 (8:00 AM – 5:00 PM)

Pay Range: $40.75 – $72.94 per hour

Rush offers exceptional rewards and benefits. Learn more at our Rush benefits page (https://(Use the "Apply for this Job" box below).).

The Clinical Research Nurse 1 (CRN
1) is a licensed nurse who delivers clinical care to research participants while supporting the conduct of clinical studies under the direction of a Principal Investigator (PI). Working as part of a multidisciplinary research team, this role assists with participant recruitment, eligibility screening, informed consent, and protocol adherence.

The CRN 1 monitors participants for changes in health status, manages adverse event reporting, and administers study medications when applicable. The nurse educates physicians and staff on study procedures and keeps the clinical team informed about protocol updates and participant status changes.

This entry‑level research nursing role requires strong foundational nursing skills, a willingness to learn clinical research regulations, and the ability to communicate with diverse participants and care teams. The nurse exemplifies Rush mission, vision and values and acts in accordance with Rush policies and procedures.

• Education:
  
  Bachelor of Science in Nursing (BSN) OR Master of Science in Nursing (MSN)
• Experience:
  
  Two years of clinical nursing practice experience required
• Licenses:
  Current State of Illinois Registered Nurse Licensure
• Certifications:
  
  Current Basic Life Support certification for Healthcare Professionals

• Regulatory Compliance Awareness – Introductory knowledge of GCP/GDP, human subject protections, and related regulations.
• Communication Skills – Ability to convey complex clinical and regulatory concepts in clear language.
• Participant Engagement – Ability to build rapport with diverse participants and peers.
• Judgment & Escalation – Demonstrated problem‑solving, critical decision‑making, and professional judgment.
• Time Management – Strong organizational skills and attention to detail.
• Teamwork & Collaboration – Works independently and within team settings.
• Flexibility – Willingness to work flexible hours and travel as required.

• Experience:
  
  Two years of experience in clinical research appropriate to study population.
• Certifications:
  
  Clinical specialty certification appropriate to study population.

• Deliver protocol‑required nursing care to research participants, including monitoring health status and documentation.
• Follow participant care plans based on protocol requirements and participant needs.
• Assess participant status and communicate follow‑up needs to the PI or interdisciplinary care team per protocol.
• Communicate study details and updates to participants, families, and interdisciplinary care team members.
• Educate interdisciplinary care teams on protocol requirements.
• Notify the PI and care team of changes in participant health status.
• Perform protocol‑defined procedures, including medication administration, clinical assessments, and sample collection under supervision.
• Ensure accurate documentation of tasks performed.
• Schedule study visits and prepare materials and source documentation per protocol.
• Remind participants of required tests or procedures.
• Review and enter data into study systems accurately and on time.
• Coordinate specimen handling and shipping; ensure compliance with sponsor and federal safety requirements.
• Recognize and report unexpected events, documentation errors, or potential deviations to appropriate staff.
• Report protocol deviations and serious adverse events to the study sponsor and IRB as applicable.
• Maintain current knowledge of disease‑specific conditions and research trends relevant to assigned studies.
• Complete all required protocol‑specific and system trainings.
• Apply ALCOA principles to ensure high‑quality documentation and data entry across systems.
• Navigates multiple systems (including OnCore, REDCap, Epic) to manage participant data, schedule visits, and support workflow accuracy.
• Review…