Postdoctoral Associate; Sharma Lab

Ann & Robert H. Lurie Children’s Hospital of Chicago provides superior pediatric care in a setting that offers the latest benefits and innovations in medical technology, research and family-friendly design. As the largest pediatric provider in the region with a 140-year legacy of excellence, kids and their families are at the center of all we do. Ann & Robert H. Lurie Children’s Hospital of Chicago is ranked in all 10 specialties by the U.S. News & World Report.

Simpson Querrey Biomedical Research Center

The Sharma Research Group (Northwestern University/Lurie Children’s Hospital; (Use the "Apply for this Job" box below).) is seeking a Postdoctoral Research Associate to develop regenerative engineering strategies for cardiovascular, gastrointestinal and urological disease states. The ideal candidate must hold a doctorate degree with a major in Bioengineering/Biomedical Engineering, Biomedical Sciences, Chemical Engineering, or a related area prior to joining. This position is a one-year term-limited position funded by a grant with the expectation of renewal beyond the initial appointment period with satisfactory performance.

This position is available immediately; however, the start date is flexible. Inclusion and cultural sensitivity are valued competencies specifically with regards to team chemistry. We are in search of a team member who can effectively interact with a varied population of diverse audiences, who shares our values and who will support the mission of the University through their work. The applicant will have at least 0-3 years of experience with the required skillset described below:

• The ability to culture cells, fabricate human organoids containing multiple cell types, and experience with organoid characterization techniques (cell viability, metabolic assays, RNA-seq, post-translational modification characterizations, and confocal imaging with quantification).
• Expertise with deriving, isolating, culturing, and evaluating novel pluripotent and multipotent stem and progenitor cells derived from a diverse group of tissues.
• Expertise with regards to quantitative morphometry derived from IHC/IF tissue staining.
• Nanomolecule design, synthesis, characterization (WAXS, SAXS, CD, HPLC, LC-MS/MS; in vitro and in vivo assessments) as demonstrated by lab publications.
• Small molecule identification via library screens; subsequent in vitro and in vivo testing directly relevant for the promotion of tissue regeneration and inflammation modulation
• Expertise with polymeric biomaterial fabrication and characterization (mechanical testing, IR, NMR) with in vivo applications, 3D programming/printing ability with in vivo applications, small and large animal handling, surgery, and maintenance.
• Strong statistical/data analysis background and expertise with statistical analyses software (R, Python, MATLAB, SAS)
• Agent-based modeling, and pharmacokinetic/pharmacodynamic (PK/PD) modeling a plus as well as any machine learning skills.
• Familiarity with soft, conformal bioelectronics.

• Provide researchers with technical assistance.
• Perform job functions adhering to principles of innovation, academic excellence and teamwork to provide the highest quality research effort to our Institution, co-workers and others.
• Conduct genetic studies, molecular biology Redcap/ Imaging software, gene chip arrays and others.
• Analyze data.
• Prepare data for presentations, grants and publications.
• Help write grant proposals and progress reports related to research projects.
• Participate in regular lab meetings, journal clubs, and research seminars.
• Perform other job functions as assigned.

• Ph.D. or MD in Medical or Biological Science Program.
• Knowledge in Computer programs, Word, Excel and PowerPoint presentations.
• Excellent writing and communication skills.
• Organizational skills:
  Ability to establish priorities and respond promptly to a large variety of requests and needs, sometimes in stressful situations.

PhD (Required)

$46,280.00-$75,670.40 Salary

At Lurie Children’s, we are committed to competitive and fair compensation aligned with market rates and internal…