Postdoctoral Research – Translational Brain Tumor Research Lee-Chang Lab

Postdoctoral Research Opportunity – Translational Brain Tumor Research in the Lee-Chang Lab

Join to apply for the Postdoctoral Research Opportunity – Translational Brain Tumor Research in the Lee-Chang Lab role at Northwestern Department of Neurological Surgery.

The Department of Neurological Surgery at Northwestern University is seeking an outstanding postdoctoral scholar for the expansion of fundamental aspects of chordoma immunology and translational research in the field of brain and spine tumor immunotherapies.

This position offers an opportunity to work in the NIH‑funded lab of Dr. Catalina Lee‑Chang
. The Lee‑Chang lab has a strong translational emphasis, relying on patient tumor specimens, clinical data, next‑generation sequencing data, and cutting‑edge technologies such as spatial proteomics multiplex immunofluorescence. The Department of Neurological Surgery offers a nurturing environment for career development, a stimulating community of several CNS tumor research labs, weekly conferences, and seminars of interest.

The postdoctoral scholar will be expected to:

• Build a publication record, including submissions to leading cancer biology journals; supervise rotating undergraduate, graduate, and medical students; apply for internal and/or extramural funding; and attend national meetings to help build an international reputation.

PhD in immunology, molecular biology, biochemistry, cancer biology, or related field.

• Experience with next‑generation sequencing data and gene expression analysis (single‑cell and spatial transcriptomics, proteomics, methylome)
• Experience working with mammalian cell culture
• Expertise in immunology‑related basic techniques, such as flow cytometry
• Ability to design and conduct experiments, maintain accurate GLP‑style record‑keeping, and collaborate effectively within a team environment
• Strong verbal and written communication skills
• Ability to prepare and present research at meetings and write scientific manuscripts in fluent English
• Strong murine and human immunology knowledge

• CRISPR, gene silencing, and over‑expression techniques
• Cloning and rescue of retroviral and lentiviral vectors

Interested applicants should send a current curriculum vitae, a cover letter containing a summary of research experience and aspirations, and names and contact information for at least three professional references to Dawn Rose. Application must include an applicant who can begin employment no later than March 1, 2026
.

Northwestern University is an Equal Opportunity, Affiliated Action Employer of all protected classes, including veterans and individuals with disabilities. Women, underrepresented racial and ethnic minorities, individuals with disabilities, and veterans are encouraged to apply. Hiring is contingent upon eligibility to work in the United States.