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Principal | Data Scientist

Job in Chicago, Cook County, Illinois, 60601, USA
Listing for: 300 Premier Healthcare Solutions, Inc.
Full Time position Listed on 2026-11-12
Job specializations:
Salary/Wage Range or Industry Benchmark: 141000 - 234000 USD Yearly USD 141000.00 234000.00 YEAR

Job Description & How to Apply Below

Principal || Data Scientist

What you will be doing:
This position will lead independent and collaborative research programs in biostatistics and health outcomes research, in partnership with public health government agencies, hospitals and health systems, and academic institutions. Apply advanced statistical and epidemiologic methods to real-world evidence (RWE) datasets, including electronic health record, administrative billing, and post-adjudicated claims data, to design observational studies, answer clinically and operationally relevant questions, and produce high-impact peer-reviewed publications.

Lead the development of statistical analysis plans and research protocols, and translate study findings into new products, services, and features that support quality improvement, population health management, and policy. A doctoral degree and considerable research experience are required. A clinical or public health background is desired, along with an understanding of how clinicians wish to deploy analytics in support of quality improvement and population health management applications.

This level is recognized as expert in their field, knowledgeable of emerging trends and industry practices. Works without supervision with complete latitude for independent judgment. May mentor less experienced peers and display leadership as needed.

Biostatistics and Epidemiology Real-World Evidence and Observational Research

Key Responsibilities

Research Leadership and Collaboration – 25% Lead research projects in collaboration with public health government agencies, hospitals and health systems, and academic institutions Translate research findings into new products, services, and features with product and engineering teams, and provide scientific leadership for large scale implementation Design, conduct, and evaluate observational studies (e.g., cohort and cross-sectional) using RWE datasets, including administrative and EHR data Work with internal and external SMEs to identify research questions that improve quality, safety, and efficiency across the healthcare system Study Design and Statistical Methodology – 25% Serve as a subject matter expert in biostatistics and epidemiology across business domains (Cost, Clinical, MDM, etc.)

Develop statistical analysis plans and research protocols for studies and strategic initiatives Apply advanced statistical methods, including GLMs, GLMMs, GAMs, ZIPs, hypothesis testing, propensity score matching, and IPW, and causal inference methods (e.g., mediation analysis, structural equation modeling) where appropriate, to produce valid and reproducible results Generate and test hypotheses and interpret study results for clinical, operational, and policy audiences Stakeholder Engagement and Research Partnerships – 15% Facilitate & lead meetings with public health agencies, health system and hospital partners, academic collaborators, and internal teams to define research questions and requirements Analyze partner needs, procedures and problems, design research approaches and make recommendations Use clinical, public health, or technical background to interpret partner needs and translate them into clinically meaningful research and products Translate research findings into features and requirements that feed product backlogs Publishing and Presentations – 20% Generate peer reviewed publications in high-impact journals as first or lead author, highlighting Premier’s research and innovative methodologies Create patent submissions to protect Premier’s intellectual property Publicly present innovative work at conferences and symposiums to demonstrate Premier’s thought Knowledge Sharing - Operations – 10% Provide statistical and research methodology advice,…

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