Bioinformatics Analyst

At Cincinnati Children’s Hospital Medical Center—consistently recognized as one of the nation’s top places to work and a global leader in pediatric research and care— we are driven by a shared commitment to discovery, collaboration, and impact. We are seeking a highly motivated Bioinformatics Analyst / Web Developer who is passionate about solving complex biological problems and clearly communicating data-driven solutions.

In this role, you will apply statistical software such as R and/or Python to analyze and visualize large-scale multiomics datasets—including single-cell RNA‑seq, ATAC‑seq, and spatial transcriptomics data—while contributing biological insight to data interpretation when applicable.

Approximately 60 % of your effort will focus on advanced single-cell and spatial data analysis, with the remaining 40 % dedicated to developing, maintaining, and enhancing modern web-based tools and databases that support data visualization and sharing. You will collaborate closely with the PI and lab team, regularly presenting progress, preparing statistical summaries, tables, figures, and reports for publications, and assisting with manuscript preparation—all while helping translate complex biological data into meaningful insights that advance lung biology research and improve outcomes for children.

This role requires a minimum of two on‑site days per week, with additional on‑site presence as needed based on business needs.

• Curates, annotates and organizes various types of biomedical data (e.g., genomic, clinical, imaging, sequencing) in flat files, relational and non-relational databases.
• Collects and records appropriate metadata.
• Ensures data are securely stored yet highly accessible to authorized users.

• Executes pipelines for curating, processing and analyzing biomedical data of various types.
• Utilizes existing software to support complex data management tasks (e.g., sequence alignment, variant calling, inter-sample comparison, patient matching/linkage).
• Utilizes web-based bioinformatics tools and public/proprietary relational databases.
• Follows standard operating procedures.
• Works in collaboration with both technology and scientific teams.

• Interfaces with clinicians/researchers to collect basic to moderate complexity requirements, including user workflows.
• Contributes to problem‑solving and solution evaluation.

• Contributes to the evaluation and development of software solutions to support basic to moderately complex data workflows.
• Under general supervision, assists with implementation and testing efforts.
• Effectively communicates the status of all efforts to necessary parties.
• Utilizes project and time‑management skills to complete projects within specific time frames.

• Contributes to analyses and publications.
• Generates reports and figures for publications.
• Assists with materials for publications and scientific meetings.
• Works closely with biostatisticians on the production of publication and presentation materials.

• Bachelor's degree in a related field.
• 0+ years of work experience in a related job discipline.

• Education & Training: Master’s or PhD in Bioinformatics, Computer Science, Statistics, Biology, or a related field.
• Programming & Tools: Proficiency in R or Python, Git Hub, and Microsoft Office; experience with analytic frameworks such as Seurat or Scanpy.
• Web Development: Strong knowledge of web technologies including HTML5, CSS, JavaScript, SQL, and R Shiny; experience in database design and web application development.
• Domain Knowledge: Background in functional genomics and basic statistics; understanding of biological systems or disease mechanisms.
• Professional
  
  Skills:
  
  Strong problem‑solving abilities; effective communication and collaboration skills; demonstrated time management and presentation capabilities.

Annualized pay may vary based on FTE status: $61,401.60 - $78,291.20.

Primary

Location:

Burnet Campus.

Schedule:

Full time, Day shift (United States of America).

Cincinnati Children’s is proud to be an Equal Opportunity Employer committed to creating an environment of dignity and respect for all our employees, patients, and families. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, age, genetic information, national origin, sexual orientation, gender identity, disability or protected veteran status. EEO/Veteran/Disability.