Postdoctoral Fellow, Cancer Biology and Bioinformatics, Kasper Lab Department

Job Overview

One full-time staff position is available in the laboratory of Dr. Susan Kasper in the Department of Environmental & Public Health Sciences, College of Medicine, University of Cincinnati.

The Kasper Laboratory integrates human primary cancer cell culture, cancer stem cell biology, mouse xenograft models, and most recently extracellular vesicles in collaboration with Dr. Somchai Chutipongtanate with multiomics technologies and bioinformatics to investigate mechanisms of prostate cancer progression and metastasis.

A leading focus is on mechanisms that drive cancer cell growth and metastasis, in particular cancer cell/tumor microenvironment interactions that regulate these processes via signals carried by extracellular vesicles, and to establish prognostic and predictive biomarkers of metastasis.

We are seeking an enthusiastic and highly self‑motivated candidate who can work both independently and cooperatively as part of a team. Candidates with a strong background in cancer biology, molecular biology, and bioinformatics are encouraged to apply. This position involves a focus on secretomes and extracellular vesicles, single‑cell sequencing analysis, and investigating the molecular mechanisms of prostate cancer metastasis and its interaction with stromal cells in the tumor microenvironment.

• Conduct cutting‑edge research on prostate cancer metastasis, focusing on molecular mechanisms, post‑translational phosphorylation, and cell‑cell interactions within the tumor microenvironment.
• Investigate the roles of secretomes and extracellular vesicles in cancer progression.
• Utilize advanced bioinformatics tools and single‑cell sequencing technologies to analyze complex datasets.
• Collaborate with a multidisciplinary team of scientists and researchers.
• Specific for the postdoctoral position:
  Disseminate research findings through publication in high‑impact journals and presentations at international conferences.

• Doctoral degree in Molecular Medicine, Cancer Biology, or a closely related field.

• Significant skills in assays for flow cytometry, Image Stream, bioassays, cellular transfections, primary cell culture from clinical biopsy samples, bioinformatics, including single‑cell or spatial sequencing analyses.
• Excellent analytical, organizational, and communication skills.
• Ability to work collaboratively in a multidisciplinary team environment.
• Specific for the postdoctoral position: a proven track record of scientific publications in relevant fields.
• Specific for the research associate position: process clinical samples, submit and make approved changes to IACUC or IRB protocols, manage mouse models for experiments, including injecting, imaging, and harvesting of mice and materials, maintain adequate stocks of lab supplies and train new research assistants, graduate students, and fellows.

• Office environment; no specific unusual physical or environmental demands.

UC offers an exceptional benefits package designed to support your well‑being, financial security, and work‑life balance. Highlights include:

• Competitive salary based on experience.
• Comprehensive health coverage (medical, dental, vision, prescription).
• Flexible spending accounts & wellness programs.
• Professional development & mentorship opportunities.

Additional benefits include comprehensive tuition remission for you and eligible dependents, robust retirement plans with UC contribution of 14–18% of salary, generous time‑off policy with vacation, sick time, 11 paid holidays, additional end‑of‑year paid time off, and 6 weeks of paid parental leave for new parents.

Building a workplace where all qualified applicants will receive consideration for employment, including Individuals with Disabilities and Protected Veterans.