Postdoctoral Researcher Positions in Structural Biology​/Biochemistry and Cell Biology

Postdoctoral Researcher Positions in Structural Biology / Biochemistry and Cell Biology

Two postdoctoral researcher positions are available in the Joiner Lab at the University of Cincinnati. We are seeking highly motivated candidates with expertise in either structural biology/biochemistry or cell/molecular biology to pursue independent and collaborative research addressing fundamental questions related to the regulation of small GTPases in organelle homeostasis and neurodegenerative disease, and the production of methane by anaerobic methanogens. Our laboratory integrates biochemical, structural, and cell-based approaches and we strive to maintain a highly collaborative research environment that values mentorship, intellectual exchange, and the professional development of all lab members.

The lab is committed to mentoring postdoctoral researchers as they develop scientific independence and prepare for career paths. Postdocs will receive regular feedback, structured mentoring, and opportunities to build skills in experimental design, communication, and leadership. We expect active participation in collaborations, manuscript preparation, grant and fellowship applications, and the mentoring of junior trainees. These are full-time positions, each initially funded for 1–2 years, with the possibility of renewal contingent on performance and funding availability.

Postdoctoral researchers will have access to state-of-the-art core facilities and institutional resources supporting professional development. This position is not eligible for H-1B sponsorship.

Essential functions include gathering and analyzing data and developing new ideas that promote current research, preparing data summaries, reports, manuscripts and presentations of research results, participating/assisting in manuscript writing for publication in scientific journals and/or presentation; keeping informed of developments in field to maintain and enhance professional expertise, lab maintenance, teaching techniques to others, training, and mentoring junior research staff. This job description can be changed at any time.

Position 1:
Structural Biology / Biochemistry Research Focus

This position will focus on illuminating the structural mechanics of these systems by using protein biochemistry, in vitro reconstitution, and structural biology approaches.

Minimum Requirements:

• PhD in Biochemistry, Structural Biology, Biophysics, or a related discipline
• Extensive experience in protein expression and purification
• Strong experimental design, data analysis, and problem-solving skills

Preferred Qualifications:

• Experience with cryo-electron microscopy, including sample preparation and/or data processing pipelines
• Experience developing and performing in vitro biochemical or biophysical assays
• Familiarity with structure–function analysis of proteins or protein complexes

Position 2:
Cell/Molecular Biology Research Focus

This position will focus on investigating cellular mechanisms of these systems using gene editing, fluorescence microscopy, and functional cell-based assays.

Minimum Requirements:

• PhD in Cell Biology, Molecular Biology, or a related discipline
• Strong experience with cell culture and cell-based assays
• Ability to independently design, execute, and interpret experiments

Preferred Qualifications:

• Experience with gene editing approaches (e.g., CRISPR/Cas-based methods)
• Experience with fluorescence microscopy, including live-cell or quantitative imaging
• Familiarity with image analysis and data quantification workflows

Application Instructions:

Applicants should submit: A brief statement describing specific interest in the Joiner lab, past research experience and technical skills, research interests broadly, and career goals; a curriculum vitae; contact information for 3 professional references. Applications will be reviewed on a rolling basis until the positions are filled.

Physical Requirements/Work Environment:
Office environment/no specific unusual physical or environmental demands.

Compensation and Benefits: UC offers an exceptional benefits package designed to support your well-being, financial security, and work-life balance. Highlights include comprehensive tuition remission, robust retirement plans, generous time-off policy, and additional benefits such as competitive salary, comprehensive health coverage, flexible spending accounts, wellness programs, professional development, and mentorship opportunities.

To apply you must create a profile and submit a complete job application through the UC applicant portal. We are unable to consider "easy apply" applications submitted via other websites. For questions about the UC recruiting process or to request accommodations with the application, please contact UC HR al Opportunity Employer.