Post Doc Fellow, Zhang Lab, UC College of Medicine, Department of Cancer Biology

Post Doc Fellow, Zhang Lab, UC College of Medicine, Department of Cancer Biology

Founded in 1819, the University of Cincinnati ranks among the nation's best urban public research universities. Home to 53,235 students, nearly 12,000 faculty and staff and 350,000+ living alumni, UC combines a Top 35 public research university with a physical setting The New York Times has called "the most ambitious campus design program in the country." With the launch of Next Lives Here, the Cincinnati Innovation District, a $100 million Jobs Ohio investment, the oldest and one of the largest cooperative education programs, a dynamic academic health center and entry into the Big 12 Conference, UC's momentum has never been stronger.

UC's annual budget stands at $1.85 billion, and its endowment totals $2 billion. UC is a mission-driven organization where we are committed to student success and positively transforming the community through scholarship and service. We thrive on innovation, making an impact, and fostering an environment where staff and faculty are key contributors to UC's success.

The UC College of Medicine has a reputation for training best-in-class healthcare professionals and developing cutting-edge procedures and research that improve the health and clinical care of patients. The Department of Cancer Biology at the University of Cincinnati has an opening for a Postdoctoral Fellow supported by NCI R01 grants to study transcriptional and epigenetic gene regulation in breast cancer metastasis and therapeutic resistance.

The Zhang laboratory currently focuses on elucidating the role and molecular mechanisms of gene- and tissue-specific transcriptional cofactors and small RNAs in liquid-liquid phase separation (LLPS) and the above processes.

We are using a combination of biochemical, molecular, genomic, and mouse genetic (conditional knockout, mutant knocking, and over-expression) approaches. We are also currently developing RNA-based nano-therapeutics to target these cofactors and small RNAs to overcome the therapeutic resistance of human breast cancer.

• Conduct research experiments in a particular field within the pre-determined research scope and methodology.
• Gather and analyze data and develop new ideas that promote current research.
• Prepare data summaries, reports, manuscripts and presentations of research results.
• Participate/assist in manuscript writing for publication in scientific journals and/or presentation; may assist in grant writing.
• Keep informed of developments in the field to maintain and enhance professional expertise.
• Lab maintenance, including equipment maintenance and ordering of supplies, as needed.
• May teach techniques to others, train, and mentor junior research staff.
• Engage in appropriate training and professional development opportunities.
• Play an active role in seeking career and research advice, both from the faculty supervisor and from other faculty members as well.
• Perform related duties based on departmental need.

Doctoral Degree in Molecular and Cellular Cancer Biology, Biochemistry, or a related field.

Prior experience with Cancer Biology, Animal Models, RNA Splicing or LLPS Biochemistry is ideal.

Office environment/no specific unusual physical or environmental demands.

UC offers an exceptional benefits package designed to support your well-being, financial security, and work-life balance. Highlights include:
Comprehensive Tuition Remission, Robust Retirement Plans, Real Work-Life Balance, and Additional Benefits Include:
Competitive salary based on experience, Comprehensive health coverage (medical, dental, vision, prescription), Flexible spending accounts & wellness programs, Professional development & mentorship opportunities.