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Senior Scientist- iPSC

Job in Cleveland, Cuyahoga County, Ohio, 44101, USA
Listing for: Trailhead Biosystems
Full Time position
Listed on 2026-08-05
Job specializations:
  • Research/Development
    Research Scientist
Salary/Wage Range or Industry Benchmark: 120000 - 180000 USD Yearly USD 120000.00 180000.00 YEAR
Job Description & How to Apply Below

Trailhead Biosystems is the pioneer of applying High-Dimensional Design-of-Experiments (HD-DoE) towards understanding systems developmental biology. Trailhead Biosystems seeks a Senior Research Scientist in the field of stem cell biology to develop industry-grade directed differentiation protocols for specialized cells within the mesodermal germ layer. The Senior Research Scientist will work in a fast-paced laboratory developing cell culture protocols of desirable phenotypes determined by company goals under guidance of R&D directors.

We are looking for an adaptable team player, armed with a growth mind set, organized and strongly focused on product development. The position involves all aspects of stem cell biology including; designing experiments, culturing the cells, protocol development and process validation. The qualified individual will report directly to the scientific directors and work with a cross-disciplinary team that includes commercial, MSAT, and manufacturing teams.

Responsibilities:
  • Design, execute and troubleshoot differentiation experiments to achieve company-wide target product profiles.
  • Train and mentor junior scientists to manage daily lab tasks with a focus of producing quality products that reach company agreed objectives.
  • Collaborate with team members and across departments to achieve defined objectives.
  • Give data presentations of results, sharing observations, opinions, and findings for open discussion between teams to ensure timely development of products
  • Prepare scientific reports for relevant stakeholders within the company.
  • Will be responsible for following and creating SOPs for developing protocols and revising according to company recommendations.
  • Work in and maintain an environment of professional integrity that is aligned with company policies.
  • Will be responsible for ensuring company’s procedures, policies, and protocols are followed within teams.
  • Maintain a safe lab environment for all by enforcing legal and organizational regulation and standards.
  • Represent the company both locally and nationally at conferences by giving poster or oral presentations.
Qualifications:
  • The ideal candidate will have a PhD in stem cell biology or applied developmental biology with a minimum of 5 years of experience, though candidates of related fields with relevant experience will be considered if they have exceptional qualifications including:
  • Comprehensive expertise in iPSC culture techniques and practices. Experience with suspension mammalian culture is a plus.
  • Experience in biomanufacturing, bioreactor cultures or related disciplines.
  • Experience with cellular and molecular assays including, RNAseq and flow cytometry. Experience with immune and blood cells is desirable.
  • Good time management and organization skills. Is detailed oriented and efficient at executing high quality experiments. Good analytical skills and data-driven.
  • Flexible and adaptable mindset willing to learn new methodologies that align with companies methodologies.
  • Willing to reprioritize efforts to meet company’s goals and deadlines.
  • Can independently thrive while working as part of a team.
  • Willing to work flexible hours as necessary.
  • Must be able to travel per project requirements less than 10% of the time.
  • Has good written and oral communication skills.
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Position Requirements
10+ Years work experience
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