Lead Infrastructure & IT Engineer

Reports to: Director, Software Engineering

Location: Remote

Delve Bio is on a mission to improve patient outcomes and lower healthcare costs by bringing cutting‑edge genomic technology to infectious diseases. We are a well‑funded biotech company backed by some of the most experienced operators and investors in the industry. Our co‑founders are highly experienced researchers, clinicians, and entrepreneurs, including Dr. Matthew Meyerson, MD. PhD (Director of Cancer Genomics at Broad Institute and co‑founder of Foundation Medicine) and Dr.

Joseph DeRisi, PhD (Professor at the University of California San Francisco and President of the Chan Zuckerberg Biohub). Delve Bio launched its flagship metagenomic next generation sequencing platform Delve Detect in 2024, providing game‑changing, infectious disease testing to patients across the US.

Our team is hiring a Lead Infrastructure & IT Engineer to help build the future for our company. As part of the Platform team, you will work across the entire development lifecycle, from idea to deployment. This fully remote role will be responsible for developing and maintaining our cloud infrastructure, security, and CI/CD pipelines. You will be working closely with our vCISO to implement security best practices.

We are looking for someone with a deep understanding of security best practices and real‑world experience implementing security processes through CI/CD. Your role will involve providing security implementations in line with HIPAA, GDPR, and NIST guidelines. You will play a key role in ensuring that software is thoroughly tested in environments that closely mirror production.

We are looking for a passionate engineer who stays up-to-date with the latest software development methodologies, security knowledge, and best practices. At our dynamic and energetic startup, your strong engineering background will be crucial as you move quickly to make an impact. This role offers significant growth potential within the organization, with opportunities to take on increased ownership across infrastructure, IT, and security as Delve Bio scales.

• Design, implement, and maintain cloud infrastructure to support business needs.
• Identify, monitor, and resolve security vulnerabilities.
• Ensure compliance through configuration as code.
• Manage identity systems, including user provisioning, group policies, and access controls
• Configure and maintain device management, compliance policies, and endpoint security
• Support general IT operations, including identity lifecycle, access requests, and endpoint troubleshooting
• Possess an understanding of change management processes, including documenting changes in compliance with regulatory standards.
• Familiarity with designing and implementing disaster recovery plans and conducting regular backups and restore testing.
• Knowledge of Compliance Automation Tools and how to triage and remediate findings.
• Support CI/CD workflows and design multipurpose tools for use across the organization.
• Collaborate with research, development, and bioinformatics teams to understand their workloads and design software and services to support them.
• Work closely with collaborators to integrate their systems with ours through software solutions.
• Participate in code reviews and testing to ensure the delivery of high‑quality software.

• Bachelor’s or Master’s degree with 4+ years of engineering experience
• Deep knowledge of AWS, GCP, and hands‑on experience with cloud computing infrastructure
• Experience managing Microsoft Entra  (Azure AD), Google Workspace, including SSO, conditional access, and role‑based access control (RBAC)
• Proficiency with Microsoft Intune, including mobile device management (MDM), mobile application management (MAM), and endpoint compliance
• Familiarity with Windows and Mac device administration and enterprise IT best practices
• Ability to implement HIPAA, GDPR, and NIST 800‑171 regulations; experience working with clinical regulated data workflows
• Experience with tools like AWS Config, Hashi Corp Sentinel, or other compliance‑as‑code solutions to automate security and compliance checks
• Experience with…