SERM Senior Scientific Director

Site Name: UK – London – New Oxford Street, Durham Blackwell Street, Upper Providence

Posted Date: Feb 13 2026

At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting‑edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success.

We’re uniting science, technology, and talent to get ahead of disease together.

Responsible to lead medical and scientific staff within the SERM (Safety Evaluation & Risk Management) and defining and driving the strategy and vision of clinical safety and pharmacovigilance activities in alignment with Global Safety business strategies. As a senior member of the Global Safety organization the role is responsible to:

• Implement policy, processes and support the implementation of operational and strategic plans.
• Ensure scientifically sound review and interpretation of data and management of safety issues and escalates safety issues identified through the safety review process to senior management and safety governance as appropriate. Makes recommendations for the further characterization, management, and communication of safety risks.
• Focus on efficiency and effectiveness to meet the needs of our Patients and HCPs. Supporting the pharmacovigilance and benefit‑risk management of the assigned portfolio of GSK global assets to ensure Patient Safety globally.

If appointed as a manager (i.e., Team/Group Leader) is responsible for leadership of a team of individual contributors. Line Management (including functional matrix reports) leadership competencies include resource and team management, coaching, influencing others, collaborative working, decision making, change management, partnership, and relations management.

• Expert in clinical safety and pharmacovigilance activities.
• Demonstrated record of sound judgement and decision making in safety evidence generation, benefit‑risk assessment, causality assessment, evaluation of safety signals, and of proactive risk management strategies including management of labelling changes, physician and patient education and monitoring of safety issues in the real world.
• Coaches and mentors SERM colleagues in the scientific/medical aspects of signal evaluation methodology and risk management and preparation of regulatory safety reports and other documents.
• Demonstrated track record of quality decision making and creative problem resolution in critical situations, based on assessment of all relevant supporting and conflicting information/factors and understanding of the wider context.
• Provides excellent medical/scientific judgment, strong analytical skills, proactive approach in drug safety and high sense of urgency.
• Champions/sponsors safety governance by development of safety strategy and its execution for products in clinical development and post marketing settings. Anticipates, detects and addresses product safety issues and ensures that risk‑reduction strategies are implemented appropriately.
• Leads cross‑GSK activities such as safety advisory panels, interfaces with and assumes ad hoc membership of a Senior Governance Committee.
• Ability to engage in, and contribute to, broad GSK environment and pharmacovigilance environment outside GSK with confidence, impact, integrity and professionalism.

• Champions/sponsors safety governance by development of safety strategy and its execution for products in clinical development and post marketing settings. Anticipates, detects and addresses product safety issues (e.g., product incidents) and ensures that risk‑reduction strategies are implemented appropriately.
• Proven ability to affect department, or product strategies with a strong understanding…