Senior Principal Statistician

We create a place where people can grow, be their best, be safe, and feel welcome, valued and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programmes, pension plan membership, and shares and savings programme.

We embrace modern work practices; our Performance with Choice programme offers a hybrid working model, empowering you to find the optimal balance between remote and in-office work.

Discover more about our company wide benefits and life at GSK on our webpage Life at GSK | GSK.

You will work within a team applying your statistical expertise and innovative methodology to support clinical development within the Oncology pipeline. You will work closely with cross‑functional teams to design studies from early first‑in‑human trials to late‑phase drug development. Our team is committed to utilising novel clinical trial designs and innovative statistical methods, including Bayesian techniques, to assess risk as well as probability of success for both studies and overall programs to enable informed decision‑making.

• Provide statistical support to Project Statisticians and support studies across Oncology pipeline
• Contribute to statistical design and analysis of clinical trials across development phases using a wide range of statistical approaches (e.g. Bayesian methodology)
• Use simulations and advanced statistical methodology to inform trial design and risk assessment. Develop and review statistical analysis plans, protocols and sample size calculations to support oncology clinical trials.
• Work closely with study teams (programmers, data managers and clinical colleagues) in support of clinical trials.
• Apply standard processes to tasks to ensure that deliverables are accurate, high quality and meet agreed timelines

Basic Qualification

• Master’s degree or higher in Statistics, Biostatistics, Applied Mathematics, Mathematics, or a related quantitative discipline.
• Demonstrated relevant industry experience.
• Practical experience in statistical programming (R, Python) and model implementation.
• Hands‑on experience with simulation methods and study design for oncology clinical development.
• Strong written and verbal communication skills for technical and non‑technical audiences.
• Proven ability to work in cross‑functional teams and to manage multiple priorities.

• PhD in Statistics or closely related field
• Experience with Bayesian methods, advanced predictive modelling, or causal inference.
• Track record of methodological innovation or contributions to publications

Closing Date for Applications – 4th March 2026

At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting‑edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success.

We’re uniting science, technology, and talent to get ahead of disease together.

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive.

We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing…