Principal BU Client Leader

McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well-being of you and those we serve – we care.

What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow’s health today, we want to hear from you.

McKesson is in the business of better health, and we touch the lives of patients in virtually every aspect of healthcare. We partner with payors, hospitals, physician offices, pharmacies, pharmaceutical companies, and others across the spectrum of care to build healthier organizations that deliver better care to patients in every setting. We believe in the importance of strong, vital organizations because we know that patients can only be healthy when our system is healthy.

Every single McKesson employee contributes to our mission—by joining McKesson you act as a catalyst in a chain of events that helps millions of people all over the globe.

We are seeking an experienced professional to join McKesson as an Enterprise Infrastructure Client Partner. This highly visible individual contributor role serves as the primary bridge between business leadership and enterprise infrastructure and platform teams.

In this role, you will ensure that infrastructure capabilities are aligned with business priorities from the outset—translating strategy into clear, actionable plans that support growth, modernization, and day‑to‑day operations. You will bring structure and clarity to how work is planned and prioritized, helping leaders make well‑informed decisions about investments, tradeoffs, and risks.

You will drive integrated planning across demand, capacity, cost, and risk—ensuring that initiatives are realistic, well‑coordinated, and positioned for successful execution. At the same time, you will provide clear visibility into infrastructure risks, performance, and key dependencies, helping the business make confident, timely decisions.

This role requires a broad understanding of enterprise infrastructure domains (such as cloud, network, platforms, and end‑user technologies) and the ability to translate technical concepts into straightforward, business‑relevant language. While you will not be responsible for designing or delivering technical solutions, you will play a critical role in aligning business and technical teams to achieve shared outcomes.

You will also serve as the primary relationship lead for the business, establishing consistent engagement, governance, and communication practices that create a seamless experience when working with enterprise infrastructure.

This is an excellent opportunity for a strategic, relationship‑focused leader who thrives at the intersection of business and technology and enjoys driving alignment, clarity, and results in a complex, fast‑paced environment.

• Build deep understanding of business unit (BU) strategy, priorities, and operating model, and translate that context across infrastructure teams to drive aligned outcomes.
• Develop and drive a multi‑year infrastructure roadmap aligned to BU strategy, integrating modernization, growth initiatives, and core operations.
• Partner with BU leadership to embed infrastructure early in planning cycles, enabling proactive engagement, clear prioritization, and value realization.
• Communicate infrastructure strategy, tradeoffs, and business impact to senior stakeholders to support informed decision‑making.
• Lead integrated planning by aligning demand, capacity, cost, and risk, ensuring decisions are transparent, governed, and clearly owned.
• Maintain a BU‑level infrastructure risk register, ensuring visibility, mitigation planning, and formal acceptance where required.
• Represent BU priorities in enterprise portfolio and capacity planning processes, surfacing resource constraints and cross‑initiative…