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Principal Investigator; MD

Job in Columbus, Franklin County, Ohio, 43224, USA
Listing for: Alliance Clinical
Full Time position
Listed on 2026-10-04
Job specializations:
  • Doctor/Physician
    Medical Doctor, Internal Medicine Physician, Oncologist
Salary/Wage Range or Industry Benchmark: 140000 - 210000 USD Yearly USD 140000.00 210000.00 YEAR
Job Description & How to Apply Below

If you are unable to complete this application due to a disability, contact this employer to ask for an accommodation or an alternative application process.

Full Time Professional Columbus, Columbus, OH, US

2 days ago Requisition

Help Build a New Clinical Research Site From the Ground Up About Alliance Clinical Network

At Alliance Clinical Network, we’re advancing medical innovation through high-quality, patient-centered clinical research. Our growing network is built around a simple belief: great research starts with great people, strong clinical leadership, and a commitment to doing what’s right for patients.

We’re looking for an Internal Medicine / Family Medicine / Specialist physician (MD/DO) with clinical research experience who wants to play a meaningful role in bringing that mission to life in Columbus, OH
.

The Opportunity

This is more than an opportunity to serve as a Principal Investigator.
It’s an opportunity to help build a new clinical research site from the ground up.

As the Principal Investigator, you’ll provide clinical and medical guidance as the site establishes itself in the community and grows its research portfolio. Your experience, clinical judgment, and perspective will help shape the site’s success while giving you the opportunity to make an impact without the demands of a traditional full-time clinical practice.

This is an especially attractive opportunity for a physician who enjoys medicine & clinical research and wants to remain clinically engaged, but is looking for a more predictable schedule; as well as the opportunity to fully contribute their time to clinical research.

Why This Opportunity Is Different

Build, don’t inherit.
Help establish a brand-new research site from the community and grows its research portfolio.

Have a meaningful voice.
Your medical expertise and clinical judgment will directly contribute to delivering a high-quality experience for participants.

Stay engaged in cutting edge medicine.
Maintain meaningful clinical involvement without the high volume / low impact environment of a traditional practice.

Bring research opportunities to local patients.
Help connect patients with clinical trials investigating new therapies and advancing the future of medicine.

Work with a team behind you.
You won’t be expected to build and manage the research operation yourself. Experienced clinical operations, regulatory, quality, and research staff provide the infrastructure and day-to-day support needed to conduct successful trials.

Grow with Alliance.
As the site develops, this role provides an opportunity to establish yourself as a key physician leader within a growing clinical research network.

What You’ll Do

As Principal Investigator, you will provide medical oversight and clinical leadership for assigned clinical trials, with patient safety and data quality at the center of your work.

  • Serve as the study physician and provide medical oversight for assigned clinical trials.
  • Protect the safety, rights, and well-being of research participants throughout the study.
  • Review and confirm participant eligibility and provide medical oversight of screening outcomes.
  • Review adverse events (AEs), serious adverse events (SAEs), and participant safety trends.
  • Perform or oversee study‑specific medical assessments, including medical histories, physical examinations, concomitant medications, and endpoint assessments.
  • Provide clinical guidance and medical oversight to Sub‑Investigators, Clinical Research Coordinators, RNs, and other site staff.
  • Serve as a clinical resource for study‑related medical questions and safety concerns.
  • Collaborate with study sponsors, CROs, IRBs, and Alliance leadership throughout the life of each trial.
  • Participate in Site Initiation Visits, monitoring visits,…
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