Post Doctoral Scholar

Overview

Post Doctoral Scholar position in the Burns laboratory, part of the Thoracic Oncology Research Collaborative Hub (TORCH). The lab focuses on targeted therapies and brain metastases in lung cancer. Extensive experience in cancer biology, in vivo studies (mouse), and molecular biology techniques is necessary; experience in metastases and/or metabolism is preferred. This role oversees two projects aiming to identify novel targeted therapies for oncogene-driven lung cancer and the treatment of brain metastases.

Projects will focus on (1) Development of targeted therapeutic strategies for oncogene-driven NSCLC through targeting EMT transcription factors and/or (2) Targeting lung cancer brain metastases through inhibition of the HGF/MET/TWIST1 pathway and metabolic dependencies. Studies will use in vitro, ex vivo and in vivo systems as well as patient samples.

• Perform molecular biology techniques, ex vivo and in vivo (mouse) studies to develop targeted approaches to overcome resistance to targeted therapies in oncogene-driven lung cancer and to develop targeted approaches for the treatment of brain metastases, with the goal of translating findings to clinical trials for NSCLC.
• Train junior staff in molecular biology techniques, ex vivo and in vivo (mouse) studies.
• Document, analyze and interpret data for presentations, manuscripts, grant requirements (current or new), etc.
• Participate in TORCH lab meetings, journal clubs and other relevant university oncology or immunotherapy meetings.
• Prepare and present at professional conferences, as well as attend to expand knowledge base and potential collaborations.

• A Doctoral degree in a biological sciences field is required; cancer biology and/or metabolism preferred.
• Experience in molecular biology techniques and in vivo work with mouse models is required.
• Requires successful completion of a background check; qualified candidates may be asked to complete a pre-employment physical including a drug screen.

• 1-2 years post-doctoral laboratory experience in cancer biology and/or cell signaling/metabolism preferred.

• A strong willingness to work in a team environment is essential.
• Contribute to TORCH with both expertise and insight into development of collaborative projects, improving upon and troubleshooting current projects.

The Ohio State University is a dynamic community of diverse resources, where opportunity thrives and where individuals transform themselves and the world. The Ohio State University is one of the nation’s largest and most comprehensive public universities and a top employer in Ohio. As one of only 54 designated comprehensive cancer centers in the nation, The Ohio State University Comprehensive Cancer Center – Arthur G.

James Cancer Hospital and Richard J. Solove Research Institute is dedicated to the creation of knowledge in laboratory, clinical and population-based cancer research. We apply those discoveries to develop more effective approaches to cancer prevention, diagnosis, and therapies – providing tomorrow’s standard of care today. A Cancer-Free World Begins Here. The OSUCCC – James is the only cancer program in the United States that features a National Cancer Institute (NCI)-designated comprehensive cancer center aligned with a nationally ranked academic medical center and a freestanding cancer hospital on the campus of one of the nation’s largest public universities.

Location:

Biomedical Research Tower (0112)

Position Type:
Term (Fixed Term)

Scheduled

Hours:

40

Shift: First Shift

Final candidates are subject to successful completion of a background check. A drug screen or physical may be required during the post offer process.

The Ohio State University and Wexner Medical Center are equal opportunity employers, including veterans and disability.

As required by Ohio Revised Code section , Ohio State will: educate students by means of free, open and rigorous intellectual inquiry to seek the truth; equip students with the opportunity to develop intellectual skills to reach their own, informed conclusions; not require, favor, disfavor or prohibit speech or lawful assembly; create a community dedicated to an ethic of civil and free inquiry, which respects the autonomy of each member, supports individual capacities for growth and tolerates differences in opinion;

treat all faculty, staff and students as individuals, hold them to equal standards and provide equality of opportunity with regard to race, ethnicity, religion, sex, sexual orientation, gender identity or gender expression.