Post Doctoral Scientist - Cardiovascular Development

Overview

Dr. Jihyun Jang at Nationwide Children’s Hospital and The Ohio State University is seeking a Fellow to study how epitranscriptomic mechanisms regulate cardiac development and congenital heart disease. Our research focuses on m6A RNA methylation and its roles in developmental cell fate decisions, congenital heart defects, and pediatric cardiomyopathies. Using human iPSC‑derived cardiac organoids, genetically engineered mouse models, CRISPR technologies, and single‑cell/multi‑omics approaches, we investigate the molecular regulation of heart development and disease.

Projects include ventricular development, congenital valve disease, endocardial biology, and pediatric cardiomyopathy. Read more about the lab here:
Jihyun Jang.

Conducts research, designs experiments, analyzes data, and presents findings under the mentorship of an established RI principal investigator or Senior Research Scientists. Appointment is a maximum of 7 years in length.

Essential Functions:

• Designs experiments, develops protocols, and conducts research under the guidance of a faculty mentor.
• Assists in the training and supervision of technical support staff in performing specific techniques essential to carrying out the research program.
• Records and analyzes data generated by the research study. Assists in the development of hypotheses for further investigation from the results of the studies performed.
• Assists with the preparation of scientific and technical papers for publication in peer‑reviewed journals. Presents findings at local and national research forums.
• Collaborates with other ongoing research efforts either at NCH or at The Ohio State University.
• Works toward research independence, preparing to submit proposals to and obtain funding from external granting agencies.

PhD or equivalent degree in relevant field of science, required.

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• Effective interpersonal skills required in interactions with scientists, physicians, and laboratory colleagues.
• Excellent laboratory technical skills.
• Excellent computer skills.
• Skills in qualitative and quantitative research methods.
• Ability to proactively manage and drive projects.

Research experience from PhD program, required.

OCCASIONALLY:
Bend/twist, Climb stairs/ladder, Lifting / Carrying: 11‑20 lbs.

FREQUENTLY:
Lifting / Carrying: 0‑10 lbs, Standing, Walking.

CONTINUOUSLY:
Audible speech, Color vision, Computer skills, Decision Making, Depth perception, Flexing/extending of neck, Hand use: grasping, gripping, turning, Hearing acuity, Interpreting Data, Peripheral vision, Problem solving, Reaching above shoulder, Repetitive hand/arm use, Seeing – Far/near, Sitting, Squat/kneel.

Pressure in this position will vary depending on the workload. The workload will be heavy but manageable most of the time. Pressure may arise in the face of deadlines associated research and manuscript writing.

EOE M/F/Disability/Vet