Research Senior Associate-Comprehensive Cancer Center

Job Title:

Research Senior Associate - Comprehensive Cancer Center

Department: CCC | Comprehensive Cancer Center

The Research Senior Associate will assist and support the center for antibody therapeutics (CAT) at the Pelotonia Institute for Immuno-Oncology (PIIO) under direct supervision of Dr. Zhiwei Hu, Managing Director of the PIIO CAT at the OSUCCC – James. The role involves planning, executing, and analyzing translational cancer research with focus on antibodies/proteins, antibody drug conjugates, bispecific antibodies, antibody‑based CAR‑NK and CAR‑T cell immunotherapy using advanced molecular, cellular, and antibody‑based techniques.

• Perform advanced in vitro and in vivo techniques including molecular biology skills such as DNA, RNA extraction, RT‑PCR, production, purification and characterization of antibodies, antibody drug conjugates, bispecific antibodies, CAR‑T, CAR‑NK and general cell culture skills such as mammalian and bacterial cell growth. Protein biochemistry such as antibody and protein purification, chromatography, SDS‑PAGE, Western blotting, ELISA, flow cytometry, immunostaining, in‑vitro assays and development, ADCC, CDC, Incu Cyte or RTCA cytotoxicity assays, biacore or other SPR assays.
• Collect, analyze, and interpret research data; assist with development and implementation of new methodologies.
• Collaborate with principal investigator to write manuscripts, abstracts and research reports for publication in peer‑reviewed journals; assist with the development and preparation of grant proposals to obtain outside funding in support of research; conduct critical analysis of research literature related to the research being investigated.
• Monitor and enforce laboratory safety procedures; ensure compliance with institutional and federal regulations.
• Train research staff and manage daily laboratory operations, including procurement and equipment maintenance.
• Perform additional duties as assigned.

• Master's Degree required, Doctor’s degree in biological or health sciences strongly preferred, or equivalent experience. 1 year of relevant experience required with Master's Degree, 3 years of relevant experience required with Bachelor's Degree.
• Ability to translate and apply academic knowledge in biological/health science research.
• Experience in antibody/protein, chromatography or antibody-based research capacity required.
• Strong analytical and communication skills.

The OSUCCC – James is the only cancer program in the United States that features a National Cancer Institute (NCI)-designated comprehensive cancer center aligned with a nationally ranked academic medical center and a freestanding cancer hospital on the campus of one of the nation’s largest public universities. Pelotonia Institute for Immuno-Oncology (PIIO) is a comprehensive bench‑to‑bedside research initiative focused on harnessing the body’s immune system to fight cancer at all levels - from prevention to treatment and survivorship.

The Center for Antibody Therapeutics (CAT) at the PIIO is a specialized technology hub dedicated to the discovery, development, production, optimization, and translation of antibody‑based therapeutics from basic science research to preclinical and clinical studies for cancer treatment. The Center leverages cutting‑edge technologies to develop monoclonal antibodies, bispecific antibodies (bsAbs), antibody‑drug conjugates (ADCs), antibody engineering, and other antibody‑based immunotherapies including CAR‑T and CAR‑NK cells, serving the PIIO research community, clinical teams, and external partners.

Biomedical Research Tower (0112)

Regular

40

First Shift

Final candidates are subject to successful completion of a background check. A drug screen or physical may be required during the post‑offer process.

The university is an equal opportunity employer, including veterans and disability.