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AI Full stack Software Engineer

Job in Columbus, Franklin County, Ohio, 43224, USA
Listing for: McKesson
Full Time position
Listed on 2026-05-24
Job specializations:
  • Software Development
    AI Engineer, Machine Learning/ ML Engineer, Software Engineer, Data Scientist
Salary/Wage Range or Industry Benchmark: 110300 - 183800 USD Yearly USD 110300.00 183800.00 YEAR
Job Description & How to Apply Below

McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well-being of you and those we serve – we care.

What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow’s health today, we want to hear from you.

AI Full Stack Software Engineer

We are seeking a highly skilled and motivated AI Full Stack Software Engineer to join our innovative team  this role, you will be instrumental in designing, developing, and deploying end-to-end AI-powered solutions that enhance our healthcare products and services. You will work across the full stack, from front-end user interfaces to back-end AI model integration and data pipelines.

Responsibilities
  • Develop and deliver AI-driven enterprise quality software applications.
  • Build scalable applications integrating Large Language Models and other AI tools (e.g. voice recognition, document parsing, image parsing, text to speech, RAG) into new and legacy codebases.
  • Design and optimize data pipelines and datasets for AI system development and testing.
  • Communicate modern AI concepts (LLMs, vector databases, etc.) to non-technical audiences.
  • Iteratively craft effective prompts to maximize LLM performance and implement prompt caching strategies.
  • Maintain prompt libraries & benchmark performance.
  • Fine-tune & serve GPT-family, Llama models.
  • Develop AI agents using Semantic Kernel.
  • Prototype co-pilot experiences & autonomous workflows.
  • Fully document all work at both the code level and application level.
  • Display the ability to learn and adapt in a changing environment.
  • Collaborate with other staff and outside stakeholders on large projects.
  • Must be passionate about creating solutions and solving complex problems.
Minimum Qualifications
  • Minimum 4+ years of experience in Software development.
  • B.S. degree in Computer Science or related engineering discipline, or equivalent experience.
Critical Skills
  • Minimum 4+ years of experience in developing AI-enhanced applications using LLMs, voice, image, or speech models.
  • Proficiency in Python and AI related python libraries such as openai, tensor flow, pytorch.
  • AI System Evaluation & Optimization:
    Proficient in sensitivity metrics (precision, recall, F1-score, AUC-ROC) and MLOps for scalable, cost-efficient AI deployment.
  • RAG Development:
    Skilled in building RAG systems from scratch or with Lang Chain/Llama Index, using vector databases for context-aware LLM applications.
  • Experience using AI coding tools (e.g. Github Copilot, Cursor, Codeium/Windsurf).
  • LLM Cost Optimization:
    Expert in managing LLM costs (token pricing, input/output rates) via prompt caching, batching, and quantization.
  • LLM Knowledge:
    Deep understanding of LLM advancements (GPT-3.5 vs GPT-4 vs o1/“thinking” models) for informed model selection and tuning.
Preferred Skills
  • Exceptional analytical skills to extract actionable insights from data.
  • Healthcare Domain Expertise, Translate clinical/business needs into AI solutions.
  • Proficiency in creating Node.js web apps (e.g. Express.js).
  • Experience with cloud (AWS/GCP/Azure).
  • Effective communication skills to collaborate with technical, Dev Ops and product management teams.
  • Experience with Git, Docker, and Kubernetes.

We are proud to offer a competitive compensation package at McKesson as part of our Total Rewards. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets. The pay range shown below is aligned with McKesson's pay philosophy, and pay will always be compliant with any applicable regulations. In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered.

For more information regarding benefits at McKesson, please consult the company’s benefits portal.

Base Pay Range for this position

$110,300 -…

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