Senior Scientist, Protein Analytics

Working with Us. Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it.

You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high‑achieving teams. Take your career farther than you thought possible. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

Read more: . At Bristol Myers Squibb, we are inspired by a single vision — transforming patients’ lives through science. In oncology, hematology, immunology, and cardiovascular disease — and with one of the most diverse and promising pipelines in the industry — each of our passionate colleagues contributes to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer.

Join us and make a difference.

We are seeking a highly skilled Senior Scientist to join our Protein Analytics team. This role is primarily bench-focused, supporting the analytical characterization of large molecule therapeutics including monoclonal antibodies, antibody‑drug conjugates (ADCs), multispecifics, and other biotherapeutics, while also managing a contractor to ensure smooth execution of laboratory activities. The successful candidate will contribute to a dynamic and collaborative group responsible for high-resolution and high-throughput analytical assays to evaluate the quality, structure, and function of drug candidates.

Based at the BMS Discovery Biotherapeutics Cambridge Crossing, MA site, you will represent the analytics function on multiple projects and collaborate closely with project teams to deliver high-quality data that informs drug discovery decisions.

• Perform detailed analytical characterization of large molecules using techniques such as LC‑MS, LC‑MS/MS, SEC‑MALS, HIC, CE‑SDS and other state‑of‑the‑art methodologies.
• Develop, optimize, and execute analytical methods for assessing purity, identity, heterogeneity, and post‑translational modifications of biotherapeutics.
• Support high‑throughput analytical workflows for early‑stage lead selection and candidate profiling.
• Maintain and troubleshoot analytical instrumentation.
• Clearly document experiments, analyze data, and present results and conclusions to project teams and stakeholders.
• Collaborate with multidisciplinary teams to support project goals and timelines.
• Manage a contractor, including task assignment, prioritization, and ensuring compliance with laboratory standards and safety practices.

• Ph.D. in Chemistry, Biochemistry, Analytical Sciences, or related discipline with 3–5 years of relevant industry experience, OR
• M.S. with 8–10 years of experience in protein analytics or biopharmaceutical characterization.
• Hands‑on experience with advanced mass spectrometry techniques such as peptide mapping, glycan profiling, drug‑to‑antibody ratio (DAR) determination, and native MS is highly desirable.
• Familiarity with automation, electronic lab notebooks, and LIMS systems.
• Strong understanding of protein structure, post‑translational modifications, and analytical method development.
• Demonstrated ability to interpret complex MS data and communicate results effectively to multidisciplinary teams.
• Excellent organizational and technical skills, with the ability to manage multiple priorities in a fast‑paced environment.
• Enthusiasm, willingness to learn, and strong work ethic.

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Compensation Overview:
C…