Associate Principle Scientist

We are seeking Senior Scientist, Antibody Characterization (SPR/BLI) to join IQVIA Laboratories at Durham, NC
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Durham, North Carolina, United States of America

$80K - $167K

The Senior Scientist will lead high‑throughput biophysical characterization of antibodies generated from discovery and affinity maturation campaigns, supporting the selection of high‑quality therapeutic leads through advanced biomolecular interaction analyses.

• Perform full biophysical characterization of antibodies from discovery and affinity maturation campaigns in a high‑throughput environment
• Supervise, train, and mentor team members in the design and execution of biomolecular interaction analyses
• Independently design, execute, and troubleshoot SPR‑ and BLI‑based assays including kinetics, affinity, blocking, competition, and epitope binning
• Analyze, interpret, and present complex data sets to support antibody lead selection across multiple concurrent programs
• Develop, optimize, and standardize novel assays to support custom antibody discovery workflows
• Collaborate with Discovery and Bioinformatics teams to guide R&D efforts related to antibody develop ability

• PhD with relevant experience or MS with 3+ years of experience in Biology, Biochemistry, Molecular Biology, Chemical Engineering, Immunology, or a related life science field, preferably within biotech or pharmaceutical environments.
• Extensive hands‑on experience with protein–protein interaction analysis using label‑free biosensor technologies
• Mastery of SPR platforms with demonstrated experience using Carterra LSA and Biacore 8K systems
• Experience with BLI instrumentation and automated laboratory systems is a plus
• Other Equivalent combination of education, training, and experience may be accepted in lieu of degree

• Strong understanding of antibody biophysical characterization and develop ability considerations
• Ability to operate, maintain, and troubleshoot complex SPR instrumentation independently
• Excellent analytical, communication, and leadership skills with the ability to manage multiple priorities

We put our employees at the center of everything we do and are committed to providing them, and their families, with benefits that meet their diverse and changing needs. We invest in integrated benefits programs and resources to take care of our employees’ physical, mental and emotional, financial and social well‑being so they can thrive at home and at work, at any stage of their well‑being journey.

To learn more about our benefits, visit

IQVIA is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, status as a protected veteran, or any other status protected by applicable law.

Company IQVIA

Location Durham, North Carolina, United States of America