Postdoctoral fellow position in immunology UT Southwestern Medical Center Job Dallas area,Texas USA,Research/Development

Position: Postdoctoral fellow position in immunology at the UT Southwestern Medical Center

Position Overview

A postdoctoral fellow position is available in the laboratory of Dr. Tuoqi Wu in the Department of Immunology and the Harold

C. Simmons Comprehensive Cancer Center at the UT Southwestern Medical Center. Ongoing projects include understanding the molecular mechanism of T‑cell stemness and exhaustion, identifying novel targets for cancer immunotherapy, and exploring age‑associated immune dysfunction in the CNS. Studies will utilize next‑generation sequencing, genome editing, bioinformatics, and molecular and cellular immunology approaches. More information at (Use the "Apply for this Job" box below).-lab

Research Focus

Dr. Wu's laboratory investigates T‑cell biology in cancer immunotherapy and aging, using cutting‑edge technologies to dissect mechanisms and develop therapeutic strategies.

Selected Publications

BACH2 dosage establishes the hierarchy of stemness and fine‑tunes antitumor immunity in CAR T cells. Nature Immunology 2026, 27(3):425-435.

Zhu Z, et al. The redox sensing KEAP1 facilitates adaptation of T cells to chronic antigen stimulation by preventing hyperactivation. Science Immunology 2024;9(101):eadk
2954.

Zhu Z, et al. FOXP1 and KLF2 reciprocally regulate checkpoints of stem‑like to effector transition in CAR T cells. Nature Immunology 2024;25(1):117-128.

Yao C, et al. BACH2 enforces the transcriptional and epigenetic programs of stem‑like CD8 T cells. Nature Immunology 2021;22(3):370-380.

Yao C, et al. Single‑Cell RNA‑Seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection. Nature Immunology 2019;20(7):890-901.

Qualifications

Candidates must hold a recent Ph.D. and/or M.D. degree. Experience in immunology, cancer biology, machine learning, cell and antibody engineering, or related fields leading to publication in peer‑reviewed journals is recommended.

Equal Opportunity Employment

UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. As an equal‑opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status.

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