Integrated Wet Lab and Computational Researcher Surgery

Why UT Southwestern?

With over 75 years of excellence in Dallas‑Fort Worth, Texas, UT Southwestern is committed to excellence, innovation, teamwork, and compassion. As a world‑renowned medical and research center, we strive to provide the best possible care, resources, and benefits for our valued employees. Ranked as the number 1 hospital in Dallas‑Fort Worth according to U.S. News & World Report, we invest in you with opportunities for career growth and development to align with your future goals.

Our highly competitive benefits package offers healthcare, PTO and paid holidays, on‑site childcare, wage, merit increases and so much more. We invite you to be a part of the UT Southwestern team where you'll discover a culture of teamwork, professionalism, and a rewarding career!

The Levi Laboratory seeks a skilled Computational Biologist I to advance cutting‑edge research in musculoskeletal trauma and biology through innovative computational approaches. In this role you will develop computational models of musculoskeletal injury, repair and regeneration using purely computational methods. You will work at the intersection of molecular biology, genetics and advanced computing technologies to uncover insights into musculoskeletal trauma and healing processes.

Key responsibilities include supporting the Principal Investigator (PI) in selecting and implementing computational methods, preparing reports for presentation or publication, and assisting with system needs for multiple research projects and labs.

• Analyze transcriptomic, single‑cell, spatial, metabolomics, proteomics, imaging, and other high‑dimensional biological datasets.
• Build reproducible Python and R workflows for preprocessing, statistical analysis, visualization, interpretation, and reporting.
• Develop predictive, machine learning/AI, and computer vision approaches for wound healing, trauma response, and tissue analysis.
• Manage laboratory computing infrastructure, including hardware, software, high‑performance computing, cloud/server workflows, databases, data management, and network troubleshooting.
• Support wet‑lab workflows, including animal handling, small animal procedures, histology, immunofluorescence imaging, CyTOF, flow cytometry, and mammalian cell culture.
• Document methods, prepare reports and presentations, contribute to publications, train lab staff on research systems, and collaborate with the PI, lab members, and external collaborators.
• Recommend and test new systems as needed; perform other duties as assigned.

• Experience with single‑cell RNA‑seq, bulk RNA‑seq, spatial transcriptomics, metabolomics, proteomics, machine learning/AI, computer vision, cloud computing, and workflow management.
• Wet‑lab experience in animal models, histology, cell biology, or molecular cell biology.

• PPO medical plan, available day one at no cost for full‑time employee‑only coverage.
• 100% coverage for preventive healthcare—no copay.
• Paid Time Off, available day one.
• Retirement programs through the Teacher Retirement System of Texas (TRS).
• Paid Parental Leave Benefit.
• Wellness programs.
• Tuition Reimbursement.
• Public Service Loan Forgiveness (PSLF) qualified employer.

• Education:
  
  Master’s Degree in Computer Science or a related field of biological science, or Bachelor’s Degree in Computer Science or a related field of biological science.
• Experience:
  
  At least 2 years of related research experience in bioinformatics and computational biology with a Bachelor’s Degree.

• Manage research laboratory computer hardware and software programming and maintenance.
• Ensure existing systems meet the continuing needs of the lab and recommend new systems as necessary.
• Perform complex data analysis related to specialized research methodologies and results as assigned by the PI.
• Develop and/or modify software to support new and ongoing research projects.
• Resolve hardware, software, and network issues in support of the lab.
• Develop and maintain complex databases to support new and ongoing research projects.
• Train laboratory staff in the use of pertinent research systems.
• May specialize in…