Research Scientist, Immunology​/Musculoskeletal Biology, Levi Lab

WHY UT SOUTHWESTERN?
With over 75 years of excellence in Dallas-Fort Worth, Texas, UT Southwestern is committed to excellence, innovation, teamwork, and compassion. As a world-renowned medical and research center, we strive to provide the best possible care, resources, and benefits for our valued employees. Ranked as the number 1 hospital in Dallas-Fort Worth according to US News & World Report, we invest in you with opportunities for career growth and development to align with your future goals.

Our highly competitive benefits package offers healthcare, PTO and paid holidays, on-site childcare, wage, merit increases and so much more. We invite you to be a part of the UT Southwestern team where you'll discover a culture of teamwork, professionalism, and a rewarding career!

Plans, coordinates, directs, and participates in work of smaller research project or major unit of large research project in field of specialization for which incumbent is particularly qualified in terms of extensive training and/or experience.

The Research Scientist will lead and support mechanistic and translational studies of osteosarcoma, with emphasis on tumor cell signaling, the tumor microenvironment, neural and neuroimmune regulation, angiogenesis, treatment response, and pulmonary metastasis. The position requires substantial scientific independence, rigorous experimental execution, and the ability to integrate in vitro, in vivo, imaging, and multiomic approaches.

The Levi laboratory in the Division of Burn, Trauma, Acute and Critical Care Surgery in the Department of Surgery has an opening for a Research Scientist with expertise in Immunology and/ or Musculoskeletal Biology. The Levi lab's mission is to improve the lives of people living with skin and musculoskeletal injuries and diseases through rigorous science and compassion. Current projects in the Levi laboratory are related to the molecular biology behind tissue fibrosis and the repair and regeneration process in tendon, muscle, and bone.

The laboratory integrates multiomics-based approaches with investigations of musculoskeletal development, homeostasis, repair, and regeneration. The laboratory uses transgenic animal models combined with bioinformatic approaches to understand the cell-cell interactions that occur within the stem cell niche under physiological conditions and strives to understand how these divergent signaling mechanisms may guide future therapeutic strategies to promote faithful repair of damaged tissue.

The Research Scientist will work under general direction to support the long-term research goals of the PI, perform sophisticated procedures to meet project needs by applying high-quality research methods and will improve existing ones as needed.

Job duties include:

• Participates in experimental design, data collection, and data analysis.
• Carries out routine molecular bench work combined with the use of animal models (animal handling, injections, surgeries, sample collection) as well as downstream processing (histology, immunofluorescent stain and confocal imaging, flow cytometry, cell culture, single cell and bulk RNA sequencing) under supervision of the PI.
• Histology, immunofluorescent stain and confocal imaging, flow cytometry, and work with cell cultures and single-cell and bulk RNA sequencing
  * Supervises laboratory personnel including students, technicians, and advanced degree holders in research techniques and protocols.
  * Develops and/or advises on the development of new approaches for achieving research goals.
  * Helps prepare data for, and assists with, writing/editing grants and manuscripts.
  * Performs other duties as assigned.

UT Southwestern is proud to offer a competitive and comprehensive benefits package to eligible employees. Our benefits are designed to support your overall wellbeing, and include:

• PPO medical plan, available day one at no cost for full-time employee-only coverage
• 100% coverage for preventive healthcare-no copay
• Paid Time Off, available day one
• Retirement Programs through the Teacher Retirement System of Texas (TRS)
• Paid Parental Leave Benefit
• Wellness programs
• Tuition Reimbursement
• Public Service Loan Forgiveness (PSLF) Qualified Employer
• Learn more about these and other UTSW employee benefits!

• Education
  PhD with major course work in the field of assignment or
  Master's Degree with major course work in the field of assignment or
  Bachelor's Degree with major course work in the field of assignment

• Experience
  5 years of research experience in the field of assignment with PhD including
  2 years at the level of Senior Research Associate or its equivalent or
  7 years of research experience in the field of assignment with Master's degree including
  3 years at the level of Senior Research Associate or its equivalent or 9 years of research experience in the field of assignment with Bachelor's degree including
  4 years Level of Senior Research Associate or its equivalent.

• Plans, organizes coordinates,…