Research Technician II - Casanova Lab

## Research Technician II – Casanova Lab Apply:
University of Texas Southwestern Medical Center:
Full time:
Posted Today:
R-4609

Primary Work Address: 6001 Forest Park Road, Dallas, TX, ## Current HHMI Employees,  to apply via your Workday account.

The Howard Hughes Medical Institute (HHMI) advances the discovery and sharing of scientific knowledge to benefit us all. As a biomedical research organization and philanthropy, HHMI supports a vibrant community of academic researchers, educators, students, and professionals. Together, we're unlocking the fundamentals of biology and building an open, inclusive future for science.
** Lab Overview
** The Laboratory of Human Genetics of Infectious Diseases, led by Dr. Jean-Laurent Casanova at UT Southwestern Medical Center, studies the human genetic and immunological determinants of life-threatening infectious diseases. The lab aims to understand why some children and adults develop life-threatening or lethal illness in the course of primary infection, while most individuals exposed to the same microbe remain unharmed.

Research in the Casanova Lab has revealed that inborn errors of immunity — genetic variants that affect a person's ability to fight off infectious agents — can confer selective vulnerability to specific severe infectious diseases. This work provides foundational support for a human genetic and immunological theory of severe infectious diseases. For more information, visit https://(Use the "Apply for this Job" box below)./
** About the Role
** We are seeking a motivated, adaptable, and team-oriented
** Research Technician II
** to join the Casanova Lab. This position is project-driven and focused on supporting research into the genetics infectious diseases, including identifying genetic mutations and conducting functional genetic analyses. The ideal candidate is a recent post-baccalaureate or early-career researcher with a background in Biology, Genetics, or Molecular Biology who is looking to gain meaningful hands-on research experience in a fast-paced, collaborative academic environment before pursuing advanced studies.

On-the-job training will be provided, and the individual will work closely with senior lab members across interdisciplinary project teams.
** What We Provide
*** A competitive compensation package with comprehensive health and wellness benefits.
* Opportunity to contribute to peer-reviewed publications, with potential co-authorship based on research contributions.
* Regular participation in lab meetings, including opportunities to present findings and develop scientific communication skills.
* Ad-hoc opportunities to attend scientific conferences and skill-specific learning events, based on performance and project relevance.
* A close-knit, collaborative lab environment where cross-team support is encouraged and teamwork is a core value.
* Access to the vibrant UT Southwestern Medical Center research community and broader scientific network.
** What You'll Do
*** Support senior lab members in day-to-day wet lab experiments focused on the genetics of infectious diseases, including functional studies and genetic analysis.
* Perform molecular biology techniques including PCR and cloning as core components of ongoing research projects.
* Apply CRISPR-based genome editing approaches, including knockout, HDR knock-in, base editing, or prime editing as project needs require.
* Assist with library design and/or cloning for high-throughput screening, viral vector production, and next-generation sequencing (NGS) preparation, depending on project assignment.
* Collect, record, and organize experimental data with accuracy and attention to detail.
* Collaborate actively with team members across both lab project teams, providing and receiving support as needed.
* Participate…