Postdoctoral Position: Spatiotemporal Mechanisms Controlling Circadian Rhythms and Sleep, Yadla

The Yadlapalli Lab in the Department of Cell and Developmental Biology has pioneered cell biological approaches that visualize individual clock mRNAs, genes, and proteins with subcellular resolution in intact Drosophila brains. We use this capability, together with fly neurogenetics, proteomics, RNA biology, multi-omics, and quantitative imaging, to ask how the spatiotemporal organization of clock components in clock neurons controls circadian rhythms.

We are recruiting a postdoctoral fellow to lead independent projects in one of the following research areas:

• Clock protein condensates and their role in circadian rhythm regulation
• Clock mRNA localization – spatiotemporal organization, targeting to RNP bodies, and the underlying regulatory mechanisms
• Chromatin accessibility at clock-controlled genes
• Sleep regulation – molecular and cellular mechanisms

Projects are designed to advance ongoing research while building toward each fellow’s future independent program.

Funding & environment. The lab is supported by NIH R35 (MIRA) and NIH R01 awards, providing stable, long-horizon funding for ambitious projects. Fellows receive direct mentorship on grant writing, publication strategy, and the academic job market, and join an active circadian/sleep community at Michigan.

• Ph.D. in neurobiology, molecular biology, cell biology, genetics, biochemistry, or a related field
• Strong interest in circadian biology, sleep, or adjacent areas
• Experience with Drosophila genetics, imaging, RNA biology, biochemistry, or omics is a plus but not required

Send a single PDF to swathi containing: (1) a cover letter describing research experience, career goals, and fit; (2) CV with publication list and a one-paragraph contribution summary for each paper; (3) names and contact information for three references.