Senior Lab Researcher - Seibold Lab

The Seibold Laboratory is seeking a passionate and highly motivated Senior Lab Researcher to join our cutting-edge, NIH-funded research team. Our group is an interdisciplinary laboratory that brings together diverse molecular and cellular skill sets to advance human translation disease research in asthma and allergic diseases. We integrate robotic, high-throughput processing of biospecimens from large human cohorts with scalable primary airway and immune cell/tissue culture models for mechanistic studies, alongside multi-omic molecular/genetic profiling to define complex disease pathobiology.

Our laboratory platforms and capabilities include:

• Robotic and automated sample processing to support high-throughput human cohort studies.
• Primary airway epithelial and immune cell culture models for mechanistic experiments.
• Advanced molecular and genetic techniques, including RNA-seq library construction, single-cell RNA-seq, and spatial transcriptomics.
• Rigorous data capture, quality control, and compliant laboratory practices to support translational research.

The Senior Lab Researcher independently performs all phases of experimental investigations and collaborate closely with principal investigators to drive the progress of major research projects. The selected candidate will serve as a technical advisor and provide guidance to laboratory technical, support, and auxiliary staff.

Preferred Qualifications:

• Experience with high-throughput workflows and/or laboratory automation (robotics).
• Experience with primary airway epithelial culture and/or immune cell culture systems.
• Hands-on experience with RNA-seq library preparation, single-cell RNA-seq, and/or spatial transcriptomics.
• Demonstrated ability to mentor staff and coordinate multi-project laboratory operations.

At National Jewish Health, the Senior Lab Researcher will contribute directly to high-impact translational discoveries within a globally recognized leader in respiratory, cardiac, immune, and related diseases. With a legacy of innovation in science and medicine since 1899, National Jewish Health offers a mission-driven environment where rigorous research is translated into meaningful advances in patient care and disease understanding. This role provides the opportunity to work alongside leading investigators in a highly collaborative setting where cutting-edge technology and scientific excellence drive progress in complex disease research.

Position Summary
The position independently performs all phases of experimental investigations and collaborates with the principal investigators in the progress of major research projects. Acts as a technical advisor to laboratory technical, support and auxiliary staff.

Essential Duties

Plans, develops, operates, records, collaborates and reports on research projects.

Performs as the technical advisor on techniques involving complex analyses utilizing highly sophisticated techniques.

Provides guidance to laboratory staff, including technicians, support and auxiliary staff.

Plans, organizes and leads the work of Lab Researchers and Lab Technicians.

Serves as the primary contact with the research staff for technical services on major techniques, recording devices and statistical procedures relative to the specifically assigned field.

Reviews quality control of new of modified laboratory techniques which may affect any part of major projects.

Performs routine and non-routine tests leading to the successful completion of developed experiments.

Prepares statistical tabulations, using a calculator or computer.

Demonstrates enhanced proficiency in data analysis, preparation of glassware, extraction and plating procedures, programming and mathematical ordering systems.

Oversees supply functions, inventory control, equipment use and maintenance, and animal care and ordering, as needed.

Ensures laboratory and staff compliance with departmental, Institution and regulatory policies

Maintains compliance with all institutional / safety training requirements.

Maintains laboratory records, supplies, samples in an organized manner (such as a laboratory notebook and sample storage record).

Other Duties & Responsibilities

Performs all other duties as assigned

Key Competencies

Laboratory Knowledge: Demonstrates and understands laboratory testing and methodology.

Decision Quality: Makes good decisions based upon a mixture of analysis, wisdom, experience, and judgment. Sought out by others for advice and solutions.

Adaptability: Maintains effectiveness in the midst of change in work responsibilities or environment, requirements ambiguity, or stress.

Problem Solving: Uses issue identification, data relation and comparison, pattern recognition and information gathering to create analyses and make recommendations.

Informing/Communicating: Conveys ideas, responses, or instructions effectively, appropriately, and persuasively through writing or speech.

Professional Relationships: Interacts with others in a constructive, positive, and respectful manner, regardless of individual…